ArticleAnnals of translational medicine2019
Non-intubated thoracoscopic surgery for lung cancer in patients with impaired pulmonary function.
Article in Annals of translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 33 citations in OpenAlex.
- Comparative analysis of safety and efficacy of non-intubation in lung wedge resection using thoracoscopy: a systematic review and meta-analysis.Journal of thoracic disease · 2026Article
- Comparative analysis of safety and outcomes of Non-intubated versus intubated uniportal video-assisted thoracic surgery using propensity score matching: a single-center experience expanding indications beyond traditional restrictions.Frontiers in surgery · 2026Article
- Cost-effectiveness and postoperative outcomes of spontaneousJournal of thoracic disease · 2024Article
- Adjuvant Transthoracic Negative-Pressure Ventilation in Nonintubated Thoracoscopic Surgery.Journal of clinical medicine · 2023Article
- Role of exosomes in non-small cell lung cancer and EGFR-mutated lung cancer.Frontiers in immunology · 2023Review
- Thoracic surgery in the non-intubated spontaneously breathing patient.Respiratory research · 2022Review
- Italian survey on non-intubated thoracic surgery: results from INFINITY group.BMC anesthesiology · 2022Article
- Spontaneous Ventilation Video-Assisted Thoracoscopic Surgery for Non-small-cell Lung Cancer Patients With Poor Lung Function: Short- and Long-Term Outcomes.Frontiers in surgery · 2022Article
- Lung Biopsy With a Non-intubated VATS Approach in an Obese Population: Indications and Results.Frontiers in surgery · 2022Article
- Non-intubated Thoracic Surgery: Wedge Resections for Peripheral Pulmonary Nodules.Frontiers in surgery · 2022Review
- Non-Intubated Thoracic Surgery: Standpoints and Perspectives.Frontiers in surgery · 2022Article
- Recent advances in non-intubated robotic-assisted thoracic surgery (NiRATS) for tracheal/airway resection and reconstruction.Annals of translational medicine · 2021Article
- Radical resection of solitary tracheal extramedullary plasmacytoma under non-intubated anesthesia: a case report.Annals of translational medicine · 2021Article
- A risk score for predicting postoperative complications in non-intubated thoracic surgery.Journal of thoracic disease · 2021Article
- A comparison of non-intubated video-assisted thoracic surgery with spontaneous ventilation and intubated video-assisted thoracic surgery: a meta-analysis based on 14 randomized controlled trials.Journal of thoracic disease · 2021Article
- Effects of Non-intubated Video-Assisted Thoracic Surgery on Patients With Pulmonary Dysfunction.Frontiers in surgery · 2021Article
- Converting to Intubation During Non-intubated Thoracic Surgery: Incidence, Indication, Technique, and Prevention.Frontiers in surgery · 2021Review
- The effect of different depths of anesthesia monitored using Narcotrend on cognitive function in elderly patients after VATS lobectomy.American journal of translational research · 2021Article
- [Advances of Exosomes Extraction and Its Mechanism in Early Diagnosis of Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2020Review
- Spontaneous ventilation video-assisted thoracic surgery for mediastinal tumor resection in patients with pulmonary function deficiency.Annals of translational medicine · 2020Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with impaired lung function or chronic obstructive pulmonary disease (COPD) are considered high-risk for intubated general anesthesia, which may preclude them from surgical treatment of their lung cancers. We evaluated the feasibility of non-intubated video-assisted thoracoscopic surgery (VATS) for the surgical management of lung cancer in patients with impaired pulmonary function.
methodsFrom August 2009 to June 2015, 28 patients with impaired lung function (preoperative forced expiratory volume in 1 second <70% of the predicted value) underwent non-intubated VATS using a combination of thoracic epidural anesthesia or intercostal nerve block, and intra-thoracic vagal block with target-controlled sedation.
resultsEighteen patients had primary lung cancers, 4 had metastatic lung cancers, and 6 had non-malignant lung tumors. In the patients with primary lung cancer, lobectomy was performed in 4, segmentectomy in 3 and wedge resection in 11, with lymph node sampling adequate for staging. One patient required conversion to intubated one-lung ventilation because of persistent wheezing and labored breathing. Five patients developed air leaks more than 5 days postoperatively while subcutaneous emphysema occurred in 6 patients. Two patients developed acute exacerbations of pre-existing COPD, and new-onset atrial fibrillation after surgery occurred in 1 patient. The median duration of postoperative chest tube drainage was 3 days while the median hospital stay was 6 days.
conclusionsNon-intubated VATS resection for pulmonary tumors is technically feasible. It may be applied as an alternative to intubated general anesthesia in managing lung cancer in selected patients with impaired pulmonary function.
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