Evidence map›Paper›PMID 30906683›Full record

ArticleIEEE access : practical innovations, open solutions2018

Structurally-sensitive Multi-scale Deep Neural Network for Low-Dose CT Denoising.

Chenyu You, Qingsong Yang, Hongming Shan, Lars Gjesteby, Guang Li, Shenghong Ju, Zhuiyang Zhang, Zhen Zhao, Yi Zhang, Cong Wenxiang and 1 more

Abstract read
In one paragraph

Article in IEEE access : practical innovations, open solutions, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chenyu YouDepartments of Bioengineering and Electrical Engineering, Stanford University, Stanford, CA, 94305.
Qingsong YangDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180.
Hongming ShanDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180.
Lars GjestebyDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180.
Guang LiDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180.
Shenghong JuJiangsu Key Laboratory of Molecular and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing 210009, China.
Zhuiyang ZhangDepartment of Radiology, Wuxi No.2 People's Hospital,Wuxi, 214000, China.
Zhen ZhaoJiangsu Key Laboratory of Molecular and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing 210009, China.
Yi ZhangCollege of Computer Science, Sichuan University, Chengdu 610065, China.
Cong WenxiangDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180.
Ge WangDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180.

Funding

High dose efficiency CT SystemU01EB017140 · NIBIB · STANFORD UNIVERSITY · PI EDIC, PETER, PELC, NORBERT J. · 2014 to 2018
$5.4M
Grating-based X-ray Phase-contrast Tomography MethodsR01EB016977 · NIBIB · RENSSELAER POLYTECHNIC INSTITUTE · PI WANG, GE · 2014 to 2017
$1.3M
Tensor-based Dictionary Learning for Imaging BiomarkersR21EB019074 · NIBIB · UNIVERSITY OF MASSACHUSETTS LOWELL · PI YU, HENGYONG · 2015 to 2016
$441k
NIBIB NIH HHS R01 EB016977NIBIB NIH HHS R21 EB019074NIBIB NIH HHS U01 EB017140
6 · The paper itself

Abstract

Computed tomography (CT) is a popular medical imaging modality and enjoys wide clinical applications. At the same time, the x-ray radiation dose associated with CT scannings raises a public concern due to its potential risks to the patients. Over the past years, major efforts have been dedicated to the development of Low-Dose CT (LDCT) methods. However, the radiation dose reduction compromises the signal-to-noise ratio (SNR), leading to strong noise and artifacts that downgrade CT image quality. In this paper, we propose a novel 3D noise reduction method, called Structurally-sensitive Multi-scale Generative Adversarial Net (SMGAN), to improve the LDCT image quality. Specifically, we incorporate three-dimensional (3D) volumetric information to improve the image quality. Also, different loss functions for training denoising models are investigated. Experiments show that the proposed method can effectively preserve structural and textural information in reference to normal-dose CT (NDCT) images, and significantly suppress noise and artifacts. Qualitative visual assessments by three experienced radiologists demonstrate that the proposed method retrieves more information, and outperforms competing methods.

Indexed as

Deep learningImage denoisingLoss FunctionLow dose CTMachine Leaning

Identifiers

PMID30906683
PMCPMC6426337

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.