Evidence map›Paper›PMID 30906588›Full record

ArticleJournal of ophthalmology2019

Therapeutic Effect of Traditional Chinese Medicine on a Rat Model of Branch Retinal Vein Occlusion.

Pan Long, Weiming Yan, Jianwen Liu, Manhong Li, Tao Chen, Zuoming Zhang, Jing An

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Naringin Suppresses CoClAntioxidants (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Potential mechanism ofPharmaceutical biology · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Pan LongCenter of Clinical Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi 710032, China.ORCID 0000-0002-1339-5596
Weiming YanDepartment of Ophthalmology, The 900th Hospital of the Logistic Team of Chinese PLA, Fuzhou, Fujian 350025, China.
Jianwen LiuCenter of Clinical Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi 710032, China.ORCID 0000-0002-5899-8059
Manhong LiDepartment of Ophthalmology of Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032, China.
Tao ChenCenter of Clinical Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi 710032, China.ORCID 0000-0002-6254-1414
Zuoming ZhangCenter of Clinical Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi 710032, China.ORCID 0000-0002-8305-5765
Jing AnInstitute of Neurobiology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China.ORCID 0000-0001-6422-2604
Air Force Medical University · CNXi'an Jiaotong University · CNXijing Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Branch retinal vein occlusion (BRVO) is a common retinal vascular disorder leading to visual impairment. Currently, the general strategies for BRVO are symptomatic therapies. Cardiovascular aspects are essential risk factors for BRVO. The traditional Chinese medicine hexuemingmu (HXMM), consisting of tanshinol and baicalin, dilates the vasculature and accelerates microcirculation. Therefore, the aim of this study was to determine the efficacy and possible mechanism of HXMM in a BRVO rat model established by laser photocoagulation. Successful BRVO rat models were treated with different doses of HXMM. Fundus photography and fluorescein fundus angiography (FFA) of the animals were applied. The retinal layers were measured by optical coherence tomography (OCT). Full-field electroretinography (ffERG) was applied to evaluate the retinal function. The ear vein flow velocity was measured via a microcirculation detector. The expression of the vascular endothelial growth factor (VEGF-

Identifiers

PMID30906588
PMCPMC6398022
OpenAlexW2916745114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.