Evidence map›Paper›PMID 30906535›Full record

ArticleF1000Research2019

Identifying stroke therapeutics from preclinical models: A protocol for a novel application of network meta-analysis.

Manoj M Lalu, Dean A Fergusson, Wei Cheng, Marc T Avey, Dale Corbett, Dar Dowlatshahi, Malcolm R Macleod, Emily S Sena, David Moher, Risa Shorr and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 3 countries.

Manoj M LaluDepartment of Anesthesiology and Pain Medicine, The Ottawa Hospital, Ottawa, Canada.ORCID 0000-0002-0322-382X
Dean A FergussonClinical Epidemiology Program, Blueprint Translational Research Group, The Ottawa Hospital Research Institute, Ottawa, Canada.
Wei ChengKnowledge Synthesis Group, Clinical Epidemiology Program, The Ottawa Hospital Research Institute, Ottawa, Canada.ORCID 0000-0002-1475-4079
Marc T AveyClinical Epidemiology Program, Blueprint Translational Research Group, The Ottawa Hospital Research Institute, Ottawa, Canada.
Dale CorbettDepartment of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Canada.
Dar DowlatshahiSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada.
Malcolm R MacleodCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Emily S SenaCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
David MoherSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada.ORCID 0000-0003-2434-4206
Risa ShorrLearning Services, The Ottawa Hospital, Ottawa, Canada.
Sarah K McCannCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Laura J GrayDepartment of Health Sciences, University of Leicester, Leicester, UK.
Michael D HillCumming School of Medicine, Clinical Neurosciences and Hotchkiss Brain Institute, University of Calgary, Calgary, Canada.ORCID 0000-0002-6269-1543
Annette O'ConnorCollege of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.ORCID 0000-0003-0604-7822
Kristina ThayerNational Institute of Environmental Health Sciences, Durham, North Carolina, USA.
Fatima HaggarClinical Epidemiology Program, Blueprint Translational Research Group, The Ottawa Hospital Research Institute, Ottawa, Canada.
Aditi DobriyalClinical Epidemiology Program, Blueprint Translational Research Group, The Ottawa Hospital Research Institute, Ottawa, Canada.
Hee Sahng ChungClinical Epidemiology Program, Blueprint Translational Research Group, The Ottawa Hospital Research Institute, Ottawa, Canada.
Nicky J WeltonDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Brian HuttonSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada.
University of Ottawa · CAOttawa Hospital · CAUniversity of Edinburgh · GBIowa State University · USNational Institute of Environmental Health Sciences · USUniversity of Bristol · GBUniversity of Calgary · CAUniversity of Leicester · GB

Funding

CIHR 365473Medical Research Council MR/M005615/1National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/L000970/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease Models, AnimalAnimalsHumansNetwork Meta-Analysis as TopicResearch DesignStrokenetwork meta-analysisnetwork metaanalysispreclinicalstrokesystematic review

Identifiers

PMID30906535
PMCPMC6426098
OpenAlexW2906793936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.