Evidence map›Paper›PMID 30906504›Full record

ArticleOxidative medicine and cellular longevity2019

Propofol Reduced Mammosphere Formation of Breast Cancer Stem Cells via PD-L1/Nanog

Xiaobei Zhang, Fangxuan Li, Ying Zheng, Xiaokun Wang, Kaiyuan Wang, Yue Yu, Hongwei Zhao

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Targeting Breast Cancer Stem Cells.International journal of biological sciences · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Identification of potential therapeutic target of naringenin in breast cancer stem cells inhibition by bioinformatics andSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Article
  16. Review
  17. Article
  18. Article
  19. International journal of nanomedicine · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xiaobei ZhangDepartment of Anesthesiology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin 300060, China.ORCID 0000-0002-9244-5669
Fangxuan LiKey Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China.ORCID 0000-0002-1188-6922
Ying ZhengDepartment of Anesthesiology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin 300060, China.ORCID 0000-0002-5264-6431
Xiaokun WangDepartment of Anesthesiology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin 300060, China.ORCID 0000-0002-7174-2007
Kaiyuan WangDepartment of Anesthesiology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin 300060, China.ORCID 0000-0002-8374-6427
Yue YuKey Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China.ORCID 0000-0003-2053-9866
Hongwei ZhaoDepartment of Anesthesiology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin 300060, China.ORCID 0000-0002-8651-0743
Tianjin Medical University Cancer Institute and Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several researches revealed that propofol, a hypnotic intravenous anesthesia agent, could inhibit the cancer cell proliferation and tumor formation, which might affect cancer recurrence or metastasis and impact patients' prognosis. Cancer stem cells (CSCs) comprised a tiny fraction of tumor bulk and played a vital role in cancer recurrence and eventual mortality. This study investigates the effect of propofol on breast cancer stem cells (BCSCs)

Indexed as

B7-H1 AntigenBreast NeoplasmsDown-RegulationFemaleHumansMCF-7 CellsNanog Homeobox ProteinNeoplastic Stem CellsPropofolRNA, Small InterferingSpheroids, CellularB7-H1 AntigenCD274 protein, humanNanog Homeobox ProteinNANOG protein, humanPropofolRNA, Small Interfering

Identifiers

PMID30906504
PMCPMC6393877
OpenAlexW2913871696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.