Evidence map›Paper›PMID 30906434›Full record

ArticleExperimental and therapeutic medicine2019

miRNA-125a modulates autophagy of thyroiditis through PI3K/Akt/mTOR signaling pathway.

Danyan Chen, Xiaolong Huang, Song Lu, Huacong Deng, Hua Gan, Rongxi Huang, Binghan Zhang

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. mTOR Signaling in Macrophages: All Depends on the Context.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Virus, Exosome, and MicroRNA: New Insights into Autophagy.Advances in experimental medicine and biology · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Regulation of autophagy by miRNAs in human diseases.The Nucleus : an international journal of cytology and allied topics · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Analysis of the Molecular Mechanisms of the Effects ofEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Danyan ChenDepartment of Endocrinology and Nephrology, The Zhongshan District of Chongqing General Hospital, Chongqing 400231, P.R. China.
Xiaolong HuangDepartment of Endocrinology and Nephrology, The Zhongshan District of Chongqing General Hospital, Chongqing 400231, P.R. China.
Song LuDepartment of Endocrinology and Nephrology, The Zhongshan District of Chongqing General Hospital, Chongqing 400231, P.R. China.
Huacong DengDepartment of Endocrinology and Nephrology, The Zhongshan District of Chongqing General Hospital, Chongqing 400231, P.R. China.
Hua GanDepartment of Endocrinology and Nephrology, The Zhongshan District of Chongqing General Hospital, Chongqing 400231, P.R. China.
Rongxi HuangDepartment of Endocrinology and Nephrology, The Zhongshan District of Chongqing General Hospital, Chongqing 400231, P.R. China.
Binghan ZhangDepartment of Endocrinology and Nephrology, The Zhongshan District of Chongqing General Hospital, Chongqing 400231, P.R. China.
First People's Hospital of Chongqing · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study examined the potential function and underlying mechanisms of microRNA-125a (miR-125a) in thyroiditis. Mice were subcutaneously administered with 100 µg porcine thyroglobulin weekly for 2 weeks to establish the thyroiditis model. Results of the

Indexed as

inflammationmicroRNA-125aphosphoinositide 3-kinase/protein kinase B/mechanical target of rampamycinthyroiditis

Identifiers

PMID30906434
PMCPMC6425124
OpenAlexW2912259476

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.