ArticleDementia and neurocognitive disorders2018
Gait Patterns in Parkinson's Disease with or without Cognitive Impairment.
Article in Dementia and neurocognitive disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06857136 (The Role of the Glymphatic System Avaluated Thourgh mr Imaging in the Diagnosis and Management of NPH), which is not on this map. Cited by 30 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of the Glymphatic System Avaluated Thourgh mr Imaging in the Diagnosis and Management of NPH
Who cites it
30 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Gait analysis methods in people with spinal cord injury: a systematic review.Journal of neuroengineering and rehabilitation · 2026Pooled it
- Exergaming Compared to Conventional Physical Exercise Interventions on Health Status in Older People with Parkinson's Disease: A Systematic Review with Meta-Analysis of Randomized Controlled Trials.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Integrating virtual reality and exergaming in cognitive rehabilitation of patients with Parkinson disease: a systematic review of randomized controlled trials.European journal of physical and rehabilitation medicine · 2022Pooled it
- Effect of Treadmill Training Interventions on Spatiotemporal Gait Parameters in Older Adults with Neurological Disorders: Systematic Review and Meta-Analysis of Randomized Controlled Trials.International journal of environmental research and public health · 2022Pooled it
- Dual-Task Effects During a Motor-Cognitive Task in Parkinson's Disease: Patterns of Prioritization and the Influence of Cognitive Status.Neurorehabilitation and neural repair · 2021Trial
- Validity and sensitivity of instrumented postural and gait assessment using low-cost devices in Parkinson's disease.Journal of neuroengineering and rehabilitation · 2020Trial
- Quantitative Analysis of Timed Up and Go Metrics Across Parkinson's Disease Severity and Their Clinical Correlations.Diagnostics (Basel, Switzerland) · 2026Article
- Cognitive Impairment Alters Cortical Adaptation and Gait Regulation During Obstacle Walking in Patients With Parkinson's Disease: Evidence From Temporal fNIRS and Gait Dynamics.Journal of movement disorders · 2026Article
- Gait Analysis for Identifying Normal Cognition, Subjective Cognitive Decline, and Mild Cognitive Impairment in Parkinson Disease: Diagnostic Study.JMIR mHealth and uHealth · 2026Article
- Walking as a Window to the Brain: Redefining Gait in Neurology.Medical sciences (Basel, Switzerland) · 2026Review
- Differences in Spatial Cognition and Motor-Cognitive Integration by Side of Onset in People with Parkinson's Disease.Brain sciences · 2026Article
- Improving Balance and Gait in Older People with Parkinson's Disease: A Randomized Controlled Trial of Technology-Assisted Rehabilitation Interventions.Bioengineering (Basel, Switzerland) · 2026Article
- Estimation of the Knee Joint with Single-Camera Smartphone.Sensors (Basel, Switzerland) · 2026Article
- Sensor-Derived Parameters from Standardized Walking Tasks Can Support the Identification of Patients with Parkinson's Disease at Risk of Gait Deterioration.Bioengineering (Basel, Switzerland) · 2026Article
- Analyzing Gait Pattern Associated With Neuropsychiatric Symptoms in Parkinson's Disease by a Comprehensive Approach.IEEE journal of translational engineering in health and medicine · 2026Article
- Dancing through time: Cognitive changes over six years of community dance in Parkinson's disease.Journal of Alzheimer's disease : JAD · 2026Observational
- Gait Patterns and Balance Impairment in Parkinson's Disease With Correlation to Disease Severity.Dementia and neurocognitive disorders · 2025Article
- Analyzing Mobility Indicators Using Machine Learning to Detect Mild Cognitive Impairment: A Systematic Scoping Review.Applied clinical informatics · 2025Article
- Evidence for the Link Between Non-Motor Symptoms, Kinematic Gait Parameters, and Physical Function in People with Parkinson's Disease.Bioengineering (Basel, Switzerland) · 2025Article
- Dual-task-related gait patterns as possible marker of precocious and subclinical cognitive alterations in Parkinson disease.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeCognitive and gait disturbance are common symptoms in Parkinson's disease (PD). Although the relationship between cognitive impairment and gait dysfunction in PD has been suggested, specific gait patterns according to cognition are not fully demonstrated yet. Therefore, the aim of this study was to investigate gait patterns in PD patients with or without cognitive impairment.
methodsWe studied 86 patients at an average of 4.8 years after diagnosis of PD. Cognitive impairment was defined as scoring 1.5 standard deviation below age- and education-specific means on the Korean version of the Mini-Mental State Examination (K-MMSE). Three-dimensional gait analysis was conducted for all patients and quantified gait parameters of temporal-spatial data were used. Relationships among cognition, demographic characteristics, clinical features, and gait pattern were evaluated.
resultsCognitive impairment was observed in 41 (47.7%) patients. Compared to patients without cognitive impairment, patients with cognitive impairment displayed reduced gait speed, step length, and stride length. Among K-MMSE subcategories, "registration," "attention/calculation," and "visuospatial function" were significantly associated with speed, step length, and stride length. However, age, disease duration, Hoehn-Yahr (HY) stage, or Unified Parkinson's Disease Rating Scale (UPDRS) motor score was not significantly related to any gait analysis parameter.
conclusionsOur present study shows that cognitive impairment is associated with slow and short-stepped gait regardless of HY stage or UPDRS motor score, suggesting that cognitive impairment may serve as a surrogate marker of gait disturbance or fall in PD patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.