Evidence map›Paper›PMID 30906320›Full record

ArticleInterdisciplinary perspectives on infectious diseases2019

Vaccine Prophylaxis of Pneumococcal Infections in Children under Conditions of Severe Flood in the Amur River Basin.

Aleksandr G Chuchalin, Gennadiy G Onishchenko, Victor P Kolosov, Olga P Kurganova, Tatiana A Zaitseva, Leonid G Manakov, Galina N Kholodok, Juliy M Perelman, Roman S Kozlov, Natalia M Ivakhnishina and 2 more

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Article in Interdisciplinary perspectives on infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Aleksandr G ChuchalinDepartment of Hospital Therapy, Pediatric Faculty, Pirogov Russian National Research Medical University, Moscow 117997, Russia.
Gennadiy G OnishchenkoRussian Academy of Sciences, Moscow 119991, Russia.
Victor P KolosovLaboratory of Prophylaxis of Nonspecific Pulmonary Diseases, Far Eastern Scientific Center of Physiology and Pathology of Respiration, Blagoveshchensk 675000, Russia.
Olga P KurganovaThe Board of the Federal Service for Surveillance in Protection of Consumer Rights and Human Well-Being in the Amur Region, Blagoveshchensk 675002, Russia.
Tatiana A ZaitsevaThe Board of the Federal Service for Surveillance in Protection of Consumer Rights and Human Well-Being in Khabarovsk Territory, Khabarovsk 680009, Russia.
Leonid G ManakovLaboratory of Prophylaxis of Nonspecific Pulmonary Diseases, Far Eastern Scientific Center of Physiology and Pathology of Respiration, Blagoveshchensk 675000, Russia.
Galina N KholodokResearch Institute of Protection of Maternity and Childhood, Far Eastern Scientific Center of Physiology and Pathology of Respiration, Khabarovsk 680022, Russia.
Juliy M PerelmanLaboratory of Prophylaxis of Nonspecific Pulmonary Diseases, Far Eastern Scientific Center of Physiology and Pathology of Respiration, Blagoveshchensk 675000, Russia.ORCID 0000-0002-9411-7474
Roman S KozlovThe Smolensk State Medical University, Smolensk 214019, Russia.ORCID 0000-0001-8728-1113
Natalia M IvakhnishinaResearch Institute of Protection of Maternity and Childhood, Far Eastern Scientific Center of Physiology and Pathology of Respiration, Khabarovsk 680022, Russia.
Olga E TrotsenkoThe Khabarovsk Research Institute of Epidemiology and Microbiology, Khabarovsk 680610, Russia.
Albina P BondarenkoThe Khabarovsk Research Institute of Epidemiology and Microbiology, Khabarovsk 680610, Russia.
Far Eastern Scientific Centre of Physiology and Pathology of Respiration Russian Academy of Medical Sciences · RUFederal Service for Surveillance on Consumer Rights Protection and Human Wellbeing · RUKhabarovsk Scientific Research Institute of Epidemiology and Microbiology · RUPirogov Russian National Research Medical University · RURussian Academy of Sciences · RUSmolensk State Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPneumococcal infection being one of the dominant causes of acute respiratory diseases and exacerbation of chronic ones is a serious problem for human health and society. The flood in the Amur river basin in the summer of 2013 created a special zone and risk conditions for the formation of respiratory pathology in the Far-Eastern region of Russia. We aimed to give clinical and epidemiological assessment of the effectiveness of vaccination programs of respiratory viral and pneumococcal infections and generalization of regional experience in the organization of a set of measures aimed at their prevention in the postflood period in the Far-Eastern region.

methodsThe monitoring program includes children aged 2 to 5 years in the amount of 4988 with risk factors for pneumococcal infection. The pneumococcal conjugate vaccine

resultsDifferences in the frequency and range of serovariants of circulating isolates of pneumococcus in the postvaccinal period and in unvaccinated children, elimination of a number of serotypes, and appearance of circulation of nonvaccinated strains were revealed. The incidence of acute respiratory diseases and pneumonia among the vaccinated population for 2 years in the region decreased by 2.5 times. The coefficient of effectiveness of vaccination according to the indicator of morbidity of children with pneumonia reaches 75-100% with direct dependence on the age of children (r=0.98).

conclusionComparative statistical analysis revealed a high degree of effectiveness of regional programs with the methods of immunoprophylaxis of pneumococcal infections.

Identifiers

PMID30906320
PMCPMC6398015
OpenAlexW2914977283

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