Evidence map›Paper›PMID 30906299›Full record

ReviewFrontiers in immunology2019

Microbiome Dependent Regulation of T

Pushpa Pandiyan, Natarajan Bhaskaran, Mangge Zou, Elizabeth Schneider, Sangeetha Jayaraman, Jochen Huehn

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 154 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
154citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

154 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Single-Cell Analysis Reveals the Soft Tissue Structure Heterogeneity Aggravates Peri-Implantitis Through MDK Signaling.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  4. Trending ileal microbiome dysbiosis over time as an early assessment of intestinal transplant rejection risk.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
    Article
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  15. Enrichment ofFrontiers in immunology · 2026
    Article
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94 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pushpa PandiyanDepartment of Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
Natarajan BhaskaranDepartment of Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
Mangge ZouExperimental Immunology, Helmholtz Centre for Infection Research, Hamburg, Germany.
Elizabeth SchneiderDepartment of Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
Sangeetha JayaramanDepartment of Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
Jochen HuehnExperimental Immunology, Helmholtz Centre for Infection Research, Hamburg, Germany.

Funding

METABOLOME ANALYSES OF SALIVA SAMPLES FROM HIV+ PATIENTS ON cARTR01DE026923 · NIDCR · CASE WESTERN RESERVE UNIVERSITY · PI Pushpa Pandiyan · 2017 to 2026
$4.5M
NIDCR NIH HHS R01 DE026923
6 · The paper itself

Abstract

Mammals co-exist with resident microbial ecosystem that is composed of an incredible number and diversity of bacteria, viruses and fungi. Owing to direct contact between resident microbes and mucosal surfaces, both parties are in continuous and complex interactions resulting in important functional consequences. These interactions govern immune homeostasis, host response to infection, vaccination and cancer, as well as predisposition to metabolic, inflammatory and neurological disorders. Here, we discuss recent studies on direct and indirect effects of resident microbiota on regulatory T cells (T

Indexed as

Immunity, MucosalIntestinal MucosaAnimalsGastrointestinal MicrobiomeHumansTh17 CellsT-Lymphocytes, Regulatoryantibioticsinflammationmicrobiomemucosamucosal immunityresident microbesTh17Treg

Identifiers

PMID30906299
PMCPMC6419713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.