Evidence map›Paper›PMID 30906183›Full record

ArticleOrganic process research & development2018

Parallel, Large-Scale, and Long Synthetic Oligodeoxynucleotide Purification Using the Catching Full-Length Sequence by Polymerization Technique.

Dhananjani N A M Eriyagama, Shahien Shahsavari, Bhaskar Halami, Bao-Yuan Lu, Fengping Wei, Shiyue Fang

Abstract read
In one paragraph

Article in Organic process research & development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dhananjani N A M EriyagamaDepartment of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.ORCID 0000-0002-3239-1566
Shahien ShahsavariDepartment of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.ORCID 0000-0001-7731-0785
Bhaskar HalamiDepartment of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.ORCID 0000-0001-8012-5767
Bao-Yuan LuNalco Champion, an Ecolab Company, 11177 S. Stadium Drive, Sugar Land, TX 77478, USA.
Fengping WeiCGeneTech, Inc., 7202 E. 87th Street, Suite#100, Indianapolis, IN 46256, USA.
Shiyue FangDepartment of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.ORCID 0000-0002-6523-7557

Funding

Synthesis of Sensitive Epitranscriptomically Modified RNAsR15GM109288 · NIGMS · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI FANG, SHIYUE · 2014 to 2024
$1.3M
NIGMS NIH HHS R15 GM109288
6 · The paper itself

Abstract

The catching by polymerization synthetic oligodeoxynucleotide (ODN) purification technique was shown to be potentially suitable for high throughput purification by purifying 12 ODNs simultaneously, to be convenient for large-scale purification by purifying at 60 μmol synthesis scale, and to be highly powerful for long ODN purification by purifying ODNs as long as 303-mer. LC-MS analysis indicated that the ODNs purified with the technique have excellent purity.

Indexed as

high throughputlarge scaleoligonucleotidepolymerizationpurificationsynthesis

Identifiers

PMID30906183
PMCPMC6428204

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.