ArticleActa orthopaedica et traumatologica turcica2019
Effects of topical tranexamic acid during open reduction and internal fixation of acetabular fractures: A retrospective study.
Article in Acta orthopaedica et traumatologica turcica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Safety and efficacy of tranexamic acid in pelvi-acetabular trauma surgery: a systematic review and meta-analysis of randomized controlled trials.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Pooled it
- Pooled it
- Is intravenous tranexamic acid effective in reduction of blood loss during pelvic and acetabular surgery?International orthopaedics · 2022Trial
- Impact of surgeon experience on patient outcomes after pelvic and acetabular fracture surgery.Patient safety in surgery · 2025Article
- Intravenous Injection of Tranexamic Acid in Patients with Pelvic Fractures: A Prospective Randomized Trial.Hip & pelvis · 2025Article
- Increased risk of adverse events following the treatment of associated versus elementary acetabular fractures: a matched analysis of short-term complications.Archives of orthopaedic and trauma surgery · 2024Article
- A prophylactic TXA administration effectively reduces the risk of intraoperative bleeding during open management of pelvic and acetabular fractures.Scientific reports · 2023Article
- Perioperative management of acetabular and pelvic fractures: evidence-based recommendations.Archives of orthopaedic and trauma surgery · 2023Review
- How does tranexamic acid affect blood transfusion and bleeding amount in pelvis-acetabulum fractures treated with open reduction and internal fixation?Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- The efficiency and safety of intravenous tranexamic acid administration in open reduction and internal fixation of pelvic and acetabular fractures.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Tranexamic acid does not affect intraoperative blood loss or in-hospital outcomes after acetabular fracture surgery.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2022Article
- As an unusual traumatic presentation, acetabular fracture and concomitant ipsilateral intertrochanteric femur fracture: a retrospective case series of 18 patients.Journal of orthopaedic surgery and research · 2020Article
- Intravenous tranexamic acid for reducing perioperative blood loss during revision hip arthroplasty: A retrospective study.Acta orthopaedica et traumatologica turcica · 2020Article
- A retrospective comparison of the conventional versus three-dimensional printed model-assisted surgery in the treatment of acetabular fractures.Acta orthopaedica et traumatologica turcica · 2020Article
- Safety and efficacy of tranexamic acid with epinephrine for prevention of blood loss following surgery for trochanteric femoral fractures.Acta orthopaedica et traumatologica turcica · 2020Article
- The effect of topical and systemic tranexamic acid on fracture healing in rats.Acta orthopaedica et traumatologica turcica · 2020Article
- Tranexamic acid use in pelvic and/or acetabular fracture surgery: A systematic review and meta-analysis.Journal of orthopaedicsArticle
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Abstract
objectiveThe aim of this study was to assess the effect of topical tranexamic acid on blood loss and transfusion rates in acetabular fracture surgery.
methodsThe medical records of 61 patients who underwent open reduction and internal fixation for acetabular fracture between 2012 and 2015 were retrospectively reviewed. The patients were divided into two groups: Group I consisted of 31 patients (19 men and 12 women, mean age: 52 ± 19 years) who received intraoperatively a topical tranexamic acid solution of 3 g and Group 2 consisted of 30 control patients (17 men and 13 women, mean age: 48 ± 24 years) who received only 0.9% saline solution. The groups were compared based on their intraoperative blood loss, Postoperative drain output at 24 and 48 h, and postoperative hemoglobin levels, and transfusion rates.
resultsThe mean intraoperative blood loss was 410 ± 100 ml in Group 1, compared to 570 ml ± 160 ml of the control group (p < 0.05). The postoperative drain output after 24 h was 210 ± 70 ml in Group 1 compared to 330 ± 90 ml of the control group (p < 0.05). The drain output at 48 h was (50 ± 20 ml) in group 1 compared to 90 ± 40 ml of the control group (p < 0.05). The transfusion rate was significantly low group 1 (42%) than the control group (97%). Hemoglobin drop was again significantly less in tranexamic acid group (2.1 ± 1.1) than the control group (3.2 ± 1.3). The nadir postoperative hemoglobin was higher in the Group 1 (10.4 ± 1.5) than the control group (9.2 ± 1.3).
conclusionTopical administration of tranexamic acid reduces intraoperative and postoperative blood loss in acetabular fracture surgery, decreasing transfusion rates. LEVEL OF EVIDENCE: Level III, Therapeutic Study.
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