Evidence map›Paper›PMID 30905596›Full record

Observational studyDiabetes research and clinical practice2019

High risk of metabolic syndrome after delivery in pregnancies complicated by gestational diabetes.

Yun Shen, Weiqin Li, Junhong Leng, Shuang Zhang, Huikun Liu, Wei Li, Leishen Wang, Huiguang Tian, Jinbo Chen, Lu Qi and 4 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Diabetes research and clinical practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Hypertension at 5 months postpartum in women with gestational diabetes.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026
    Observational
  7. Article
  8. Kidney Dysfunction Following Gestational Diabetes Mellitus.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Article
  9. Prediction of metabolic syndrome following a first pregnancy.American journal of obstetrics and gynecology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Adverse Pregnancy Outcomes and Future Metabolic Syndrome.Journal of women's health (2002) · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 4 countries.

Yun ShenPennington Biomedical Research Center, Baton Rouge, LA, USA; Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Six People's Hospital, Shanghai, China.
Weiqin LiTianjin Women's and Children's Health Center, Tianjin, China.
Junhong LengTianjin Women's and Children's Health Center, Tianjin, China.
Shuang ZhangTianjin Women's and Children's Health Center, Tianjin, China.
Huikun LiuTianjin Women's and Children's Health Center, Tianjin, China.
Wei LiTianjin Women's and Children's Health Center, Tianjin, China.
Leishen WangTianjin Women's and Children's Health Center, Tianjin, China.
Huiguang TianTianjin Women's and Children's Health Center, Tianjin, China.
Jinbo ChenDepartment of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Lu QiDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA.
Xilin YangDepartment of Epidemiology, School of Public Health, Tianjin Medical University, Tianjin, China.
Zhijie YuPopulation Cancer Research Program, Dalhousie University, Halifax, NS, Canada.
Jaakko TuomilehtoDepartment of Public Health, University of Helsinki, Helsinki, Finland.
Gang HuPennington Biomedical Research Center, Baton Rouge, LA, USA. Electronic address: gang.hu@pbrc.edu.
Tianjin Children's Hospital · CNPennington Biomedical Research Center · USDalhousie University · CATianjin Medical University · CNTulane University · USUniversity of Helsinki · FIUniversity of Pennsylvania · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI JUDD E SHELLITO · 2012 to 2026
$69.1M
Methylomics of prenatal GDM: Natural history & lifestyle intervention in childrenR01DK100790 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI BACCARELLI, ANDREA, HOU, LIFANG · 2014 to 2017
$2.6M
NIDDK NIH HHS R01 DK100790NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

aimsTo investigate the risk of postpartum metabolic syndrome in women with GDM compared with those without GDM in a Chinese population.

methodsTianjin GDM observational study included 1263 women with a history of GDM and 705 women without GDM. Multivariate logistic regression was used to assess risks of postpartum metabolic syndrome between women with and without GDM. Postpartum metabolic syndrome was diagnosed by two commonly used criteria.

resultsDuring a mean 3.53 years of follow up, 256 cases of metabolic syndrome were identified by using the NCEP ATPIII criteria and 244 cases by using the IDF criteria. Multivariable-adjusted odds ratios of metabolic syndrome in women with GDM compared with those without GDM were 3.66 (95% confidence interval [CI] 2.02-6.63) for NCEP ATPIII criteria and 3.90 (95% CI 2.13-7.14) for IDF criteria. Women with GDM had higher multivariable-adjusted odds ratios of central obesity, hypertriglyceridemia, and high blood pressure than women without GDM. The multivariable-adjusted odds ratios of low HDL cholesterol and hyperglycemia were not significant between women with and without GDM, however, the multivariable-adjusted odds ratio of hyperglycemia became significant when we used the modified criteria.

conclusionsThe present study indicated that women with prior GDM had significantly higher risks for postpartum metabolic syndrome, as well as its individual components.

Indexed as

AdultDiabetes, GestationalFemaleHumansIncidenceMetabolic SyndromeObesityPostpartum PeriodPregnancyPrognosisRisk FactorsUnited StatesGestational diabetes mellitusMetabolic syndromePostpartum

Identifiers

PMID30905596
PMCPMC6525054
OpenAlexW2924049993

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.