Evidence map›Paper›PMID 30905419›Full record

ArticleThe Journal of thoracic and cardiovascular surgery2020

A turbulence in vitro assessment of On-X and St Jude Medical prostheses.

Hoda Hatoum, Pablo Maureira, Lakshmi Prasad Dasi

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of thoracic and cardiovascular surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
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  8. Observational
  9. Atrial and ventricular flows across a transcatheter mitral valve.Interactive cardiovascular and thoracic surgery · 2021
    Article
  10. The hemodynamics of transcatheter aortic valves in transcatheter aortic valves.The Journal of thoracic and cardiovascular surgery · 2021
    Article
  11. Impact of superhydrophobicity on the fluid dynamics of a bileaflet mechanical heart valve.Journal of the mechanical behavior of biomedical materials · 2020
    Article
  12. Article
  13. In-vitro characterization of self-expandable textile transcatheter aortic valves.Journal of the mechanical behavior of biomedical materials · 2020
    Article
  14. In vitro hemodynamic assessment of a novel polymeric transcatheter aortic valve.Journal of the mechanical behavior of biomedical materials · 2019
    Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Hoda HatoumDepartment of Biomedical Engineering, The Ohio State University, Columbus, Ohio.
Pablo MaureiraDepartment of Cardiovascular Surgery, CHU de Nancy, Nancy, France.
Lakshmi Prasad DasiDepartment of Biomedical Engineering, The Ohio State University, Columbus, Ohio. Electronic address: lakshmi.dasi@osumc.edu.
The Ohio State University · USCentre Hospitalier Régional et Universitaire de Nancy · FR

Funding

Superhydrophobic Heart Valve ProsthesisR01HL135505 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD, KOTA, ARUN KUMAR · 2017 to 2020
$2.9M
Hyaluronan enhanced polymeric heart valve prosthesisR01HL119824 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD · 2013 to 2017
$1.7M
Superomniphobic flow controlled prosthetic heart valveR21HL139208 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD, KOTA, ARUN KUMAR · 2018 to 2019
$408k
Cost Effective Trileaflet BioPolymeric Heart Valve For IndiaR03EB014255 · NIBIB · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD, JAMES, SUSAN P · 2015 to 2016
$244k
NHLBI NIH HHS R01 HL119824NHLBI NIH HHS R01 HL135505NHLBI NIH HHS R21 HL139208NIBIB NIH HHS R03 EB014255
6 · The paper itself

Abstract

objectiveThe objective of this study was to investigate and compare the hemodynamic and turbulence characteristics upon implantation of St Jude Medical (SJM) (St Jude Medical, St Paul, Minn) and On-X (On-X Life Technologies, Kennesaw, Ga) bileaflet mechanical valves. Both valves are considered highly successful bileaflet mechanical valves characterized by good clinical outcomes despite their numerous design differences. Although thromboembolism remains the main disadvantage of bileaflet mechanical valves, On-X valves have been shown to need less anticoagulation therapy.

methodsHemodynamic assessment of a 23-mm On-X bileaflet mechanical valve and a 23-mm bileaflet SJM valve implanted in an aortic root was performed under pulsatile physiologic conditions. Time-resolved and phase-locked particle-image-velocimetry images and high-speed imaging data were acquired. Pressure gradients, effective orifice areas, dimensionless area index, leaflet position tracking, velocity, and principal Reynolds shear stress were calculated.

resultsPressure gradient for the On-X valve was 4.15 ± 0.099 mm Hg versus 4.75 ± 0.048 mm Hg for SJM (P < .001). Effective orifice area for the On-X valve was 2.61 ± 0.045 cm

conclusionsThis study shows that despite the design differences that characterize the On-X valve, the hemodynamic and turbulence parameters were not necessarily improved compared with SJM.

Indexed as

anticoagulationblood damageblood thinnersmechanical valvesON-Xopen heart surgeryReynold shear stressesSJMsurgical aortic valvesturbulence

Identifiers

PMID30905419
PMCPMC6703975
OpenAlexW2916572747

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.