ArticleJournal of the American Chemical Society2019
Sulfonamide Synthesis through Electrochemical Oxidative Coupling of Amines and Thiols.
Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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Who cites it
34 citing papers in PubMed, 209 citations in OpenAlex.
- A Modular Synthesis of C5-Sulfenyl Thiazoles via an Intermolecular Pummerer Rearrangement: An Underexplored Scaffold for Medicinal Chemistry.Angewandte Chemie (International ed. in English) · 2026Article
- Heterogeneous Indirect Redox Electrocatalysis in Electrolyte.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Modular Rh-Catalyzed Synthesis and Biological Profiling of Diverse Pentafluorobenzenesulfonamide Reactive Fragments.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Anode-induced arylthiol-amine cross-coupling: A nontraditional strategy to access sulfinamides.Science advances · 2026Article
- Sustainable Approaches for the Protection and Deprotection of Functional Groups.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Review
- Article
- Electrochemical Conversions of Sulfenamides into Sulfonimidoyl- and Sulfondiimidoyl Fluorides.JACS Au · 2025Article
- Recent Advances in the Synthesis of Benzo[Molecules (Basel, Switzerland) · 2025Review
- Scaling Organic Electrosynthesis: The Crucial Interplay between Mechanism and Mass Transport.ACS central science · 2025Article
- Metal-free introduction of primary sulfonamide into electron-rich aromatics.Chemical science · 2024Article
- Electrocatalytic continuous flow chlorinations with iodine(I/III) mediators.Nature communications · 2024Article
- An efficient and mild oxidative approach from thiols to sulfonyl derivatives with DMSO/HBr.Chemical science · 2023Article
- Electrochemical Late-Stage Functionalization.Chemical reviews · 2023Review
- Wireless Electrochemical Reactor for Accelerated Exploratory Study of Electroorganic Synthesis.ACS central science · 2023Article
- Recent advances in the electrochemical reactions of nitrogen-containing organic compounds.RSC advances · 2022Review
- The advent of electrophilic hydroxylamine-derived reagents for the direct preparation of unprotected amines.Chemical communications (Cambridge, England) · 2022Review
- Electrochemical aromatic C-H hydroxylation in continuous flow.Nature communications · 2022Article
- Photochemical and Electrochemical Applications of Proton-Coupled Electron Transfer in Organic Synthesis.Chemical reviews · 2022Review
- Photons or Electrons? A Critical Comparison of Electrochemistry and Photoredox Catalysis for Organic Synthesis.Chemical reviews · 2022Review
- Dehydrogenative Azolation of Arenes in a Microflow Electrochemical Reactor.The Journal of organic chemistry · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sulfonamides are key motifs in pharmaceuticals and agrochemicals, spurring the continuous development of novel and efficient synthetic methods to access these functional groups. Herein, we report an environmentally benign electrochemical method which enables the oxidative coupling between thiols and amines, two readily available and inexpensive commodity chemicals. The transformation is completely driven by electricity, does not require any sacrificial reagent or additional catalysts and can be carried out in only 5 min. Hydrogen is formed as a benign byproduct at the counter electrode. Owing to the mild reaction conditions, the reaction displays a broad substrate scope and functional group compatibility.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.