Evidence map›Paper›PMID 30905131›Full record

ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2019

Effect of Maternal Depression on Brain-derived Neurotrophic Factor Levels in Fetal Cord Blood.

Erdem Onder Sonmez, Faruk Uguz, Mine Sahingoz, Gulsum Sonmez, Nazmiye Kaya, Mehmet Akif Camkurt, Zeynel Gokmen, Mustafa Basaran, Kazim Gezginc, Sami Sait Erdem and 2 more

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In one paragraph

Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Erdem Onder SonmezDepartment of Psychiatry, Dr. Ekrem Tok Mental Health and Disease Hospital.
Faruk UguzDepartment of Psychiatry.
Mine SahingozDepartment of Psychiatry.
Gulsum SonmezDepartment of Pediatrics, Çukurova University.
Nazmiye KayaDepartment of Psychiatry.
Mehmet Akif CamkurtDepartment of Psychiatry, Afşin State Hospital.
Zeynel GokmenDepartment of Neonatology.
Mustafa BasaranDepartment of Obstetrics and Gynecology.
Kazim GezgincDepartment of Obstetrics and Gynecology.
Sami Sait ErdemDepartment of Biochemistry, Konya Research and Training Hospital.
Hasan Haluk DulgerDepartment of Biochemistry, Meram Faculty of Medicine, Necmettin Erbakan University.
Erkan TasyurekDepartment of Biochemistry, Meram Faculty of Medicine, Necmettin Erbakan University.
Necmettin Erbakan University · TRCukurova University · TRKonya Eğitim ve Araştırma Hastanesi · TRState Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objective: We aimed to assess the association between cord blood brain-derived neurotrophic factor (BDNF) concentration and maternal depression during pregnancy.

methods: A total of 48 pregnant women, admitted for elective caesarean section to Department of Obstetrics and Gynecology, The Konya Research and Training Hospital and Konya Necmettin Erbakan University Meram Medical Faculty, were included in this study. The study group included 23 women diagnosed as having depression during pregnancy and the control group included 25 pregnant women who did not experience depression during pregnancy.

results: The groups had similar sociodemographic characteristics. Cord blood BDNF concentration was significantly lower in babies born to mothers with major depression as compared with those in the control group. We didn’t find any correlation between the umbilical cord blood BDNF levels and BDI scores.

conclusion: The results suggest that the existence of major depression in pregnant women may negatively affect fetal circulating BDNF levels.

Indexed as

Brain-derived neurotrophic factorDepressionFetal cord bloodNeurodevelopmentPregnancy

Identifiers

PMID30905131
PMCPMC6478092
OpenAlexW2921488837

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.