Evidence map›Paper›PMID 30905090›Full record

ArticleThe Prostate2019

Expression of tSTAT3, pSTAT3

Agnieszka Krzyzanowska, Nicholas Don-Doncow, Felicia Elena Marginean, Alexander Gaber, R William Watson, Rebecka Hellsten, Anders Bjartell

Open access · hybridAbstract read
In one paragraph

Article in The Prostate, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Expression of tSTAT3, pSTAT3The Prostate · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Agnieszka KrzyzanowskaDepartment of Translational Medicine, Division of Urological Cancers, Lund University, Malmö, Sweden.ORCID 0000-0002-1288-7054
Nicholas Don-DoncowDepartment of Translational Medicine, Division of Urological Cancers, Lund University, Malmö, Sweden.ORCID 0000-0003-0401-9983
Felicia Elena MargineanDepartment of Translational Medicine, Division of Urological Cancers, Lund University, Malmö, Sweden.
Alexander GaberDepartment of Clinical Sciences, Division of Pathology, Lund University, Lund, Sweden.
R William WatsonUCD School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland.
Rebecka HellstenDepartment of Translational Medicine, Division of Urological Cancers, Lund University, Malmö, Sweden.ORCID 0000-0002-3735-5636
Anders BjartellDepartment of Translational Medicine, Division of Urological Cancers, Lund University, Malmö, Sweden.
Lund University · SEMalmö University · SEUniversity College Dublin · IE

Funding

Science Foundation Ireland 15/IA/3104Wellcome Trust
6 · The paper itself

Abstract

backgroundThe signal transducer and activator of transcription 3 (STAT3) pathway is observed to be constitutively activated in several malignancies including prostate cancer (PCa). In the present study, we investigated the expression of total STAT3 (tSTAT3) and two forms of activated phosphorylated STAT3 (pSTAT3

methodsThe expression of tSTAT3, pSTAT3

resultsThe nuclear expression levels of tSTAT3, pSTAT3

conclusionsLow pSTAT3

Indexed as

AgedBiomarkers, TumorEpithelial CellsHumansMaleMiddle AgedPhosphorylationProstateProstatectomyProstatic NeoplasmsSTAT3 Transcription FactorTissue Array AnalysisBiomarkers, TumorSTAT3 protein, humanSTAT3 Transcription Factorbiomarkerimmunohistochemistryprostate cancersignal transducer and activator of transcription 3tissue microarray

Identifiers

PMID30905090
PMCPMC6766958
OpenAlexW2929101328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.