Evidence map›Paper›PMID 30905025›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2019

Metastatic pattern and prognosis of gastrointestinal stromal tumor (GIST): a SEER-based analysis.

D Y Yang, X Wang, W J Yuan, Z H Chen

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In one paragraph

Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Role of cytoreductive surgery in the management of peritoneal metastases for gastrointestinal stromal tumors.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

D Y YangDepartment of General Surgery, Xiangya Hospital of Central South University, #87 Xiangya Road, Changsha, 410008, Hunan Province, People's Republic of China.ORCID http://orcid.org/0000-0002-7047-1372
X WangDepartment of General Surgery, Shijitan Hospital of Capital Medical University, Beijing, China.
W J YuanDepartment of General Surgery, Xiangya Hospital of Central South University, #87 Xiangya Road, Changsha, 410008, Hunan Province, People's Republic of China.
Z H ChenDepartment of General Surgery, Xiangya Hospital of Central South University, #87 Xiangya Road, Changsha, 410008, Hunan Province, People's Republic of China. zihuac@outlook.com.ORCID http://orcid.org/0000-0003-2059-4443

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis SEER-based study aimed to explore and analyze the relationship of metastasis of liver, lung and bone of GIST patients and their prognosis.

methodsThe data of GIST patients were from Surveillance, Epidemiology, and End Results (SEER) database from 2010 to 2015 and all the statistical analyses were conducted by statistical software package SPSS (Version 22.0).

resultsA total of 4224 GIST patients were identified, of which 388 (9.19%) patients with liver metastasis, 20 (0.47%) patients with bone metastasis and 32 (0.76%) patients with lung metastasis. There was no significant difference of risk of bone or lung metastasis between patients with and without liver metastasis (P = 0.935). The median overall survival of patients with liver, bone, or lung metastasis was, respectively, 49 months, 18 months, and 20 months, which were all shorter than that of patients without metastasis. The overall survival of patients with both liver and bone metastasis and those with metastasis of all three sites was not significantly different from that of patients with only liver metastasis. The multivariate analysis showed age of less than 65 years, female patients, married status and receiving surgery were all the beneficial factors for prognosis of GIST patients with liver metastasis.

conclusionsPatients with metastasis had a poorer prognosis than those without. Liver metastasis might have no relationship with bone or lung metastasis and liver might play a more dominant role than the other two sites in the prognosis of GIST patients with metastasis. So, more attention should be paid to liver status in diagnosis and treatment of GIST patients.

Indexed as

AgedBone NeoplasmsFemaleGastrointestinal Stromal TumorsHumansLiver NeoplasmsLung NeoplasmsMaleMiddle AgedMultivariate AnalysisPrognosisRisk FactorsSEER ProgramTime FactorsGastrointestinal stromal tumorMetastasisPrognosisSEER

Identifiers

PMID30905025

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.