ArticleCytotechnology2019
Boron mediated 2D and 3D cultures of adipose derived mesenchymal stem cells.
Article in Cytotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Janus bilayer coating of functional quaternized chitosan and borate bioactive glass for antibacterial protection and osseointegration.Biomaterials advances · 2026Article
- Thickness-Tunable Bilayer PBAT Nanofibrous Scaffolds for Enhancing r-AdMSCs' Tenogenic Commitment in Supraspinatus Tendon Regeneration.Journal of functional biomaterials · 2026Article
- Early Biological Response to Poly(ε-caprolactone) PCL-Bioactive Glass Composites Obtained by 3D Printing as Bone Substitutes.Polymers · 2025Article
- Boron-containing compounds as labels, drugs, and theranostic agents for diabetes and its complications.World journal of diabetes · 2024Article
- Boron-Containing Compounds for Prevention, Diagnosis, and Treatment of Human Metabolic Disorders.Biological trace element research · 2023Review
- Biological nerve conduit model with de-epithelialized human amniotic membrane and adipose-derived mesenchymal stem cell sheet for repair of peripheral nerve defects.Cell and tissue research · 2023Article
- Bioactive Chitosan-Based Organometallic Scaffolds for Tissue Engineering and Regeneration.Topics in current chemistry (Cham) · 2022Review
- Photobiomodulation combined with adipose-derived stem cells encapsulated in methacrylated gelatin hydrogels enhances in vivo bone regeneration.Lasers in medical science · 2022Article
- Scaffolds from medical grade chitosan: A good choice for 3D cultivation of mesenchymal stem cells.Turkish journal of biology = Turk biyoloji dergisi · 2022Article
- Bioactive borate glass triggers phenotypic changes in adipose stem cells.Journal of materials science. Materials in medicine · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Boron (B), which is a beneficial bioactive element for human, has an increasing interest in tissue engineering for the last 5 years. However, the effective B concentration in cell culture is still unknown. The aim of the present study is to investigate in vitro osteogenic potential of mesenchymal stem cells, isolated from adipose tissue (AdMSCs), on boron containing 2D and 3D cell cultures. At first, the effects of B concentrations between 1 and 20 μg/mL were evaluated on the survival and osteogenic differentiation of AdMSCs cultured on 2D cell cultures. The 3D cultures were established by using chitosan (Ch) scaffolds prepared by freeze-drying and Ch scaffolds combined with hydroxyapatite (HAp) and B containing hydroxyapatite (B-HAp) that are produced by microwave-induced biomimetic method. The proliferation and osteogenic differentiation of AdMSCs on Ch, HAp/Ch and B-HAp/Ch scaffolds were investigated by in vitro cell culture studies. The results were evaluated with respect to cell viability, bone related ECM gene expressions, and cellular morphology. It was demonstrated that cellular functions of AdMSCs were enhanced by boron in both 2D and 3D cultures. Especially, B-HAp/Ch scaffolds, which have both osteoinductive and osteoconductive properties based on presence of B and HAp in its structure, promoted adhesion, proliferation and osteogenic differentiation of AdMSCs.
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