Evidence map›Paper›PMID 30904997›Full record

ArticleEndocrine2019

Comparison of stress response following microwave ablation and surgical resection of benign thyroid nodules.

Shu-Yan Liu, Wei-Hong Guo, Bo Yang, Yong-Feng Li, Xiao-Yun Huang, Xiao-Qing Wang, Jie Chen, Dan Xue, Xue-Hong Zhou

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Endocrine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  3. Article
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  5. Article
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  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shu-Yan LiuDepartment of Endocrinology, The First Affiliated Hospital of Henan Polytechnic University (Jiaozuo Second People's Hospital), 454000, Jiaozuo, China.
Wei-Hong GuoDepartment of Ultrasound Medicine, The First Affiliated Hospital of Henan Polytechnic University (Jiaozuo Second People's Hospital), 454000, Jiaozuo, China.
Bo YangDepartment of Neurology, The First Affiliated Hospital of Henan Polytechnic University (Jiaozuo Second People's Hospital), 454000, Jiaozuo, China.
Yong-Feng LiDepartment of Endocrinology, The First Affiliated Hospital of Henan Polytechnic University (Jiaozuo Second People's Hospital), 454000, Jiaozuo, China.
Xiao-Yun HuangDepartment of Ultrasound Medicine, The First Affiliated Hospital of Henan Polytechnic University (Jiaozuo Second People's Hospital), 454000, Jiaozuo, China.
Xiao-Qing WangDepartment of Endocrinology, The First Affiliated Hospital of Henan Polytechnic University (Jiaozuo Second People's Hospital), 454000, Jiaozuo, China.
Jie ChenDepartment of Endocrinology, The First Affiliated Hospital of Henan Polytechnic University (Jiaozuo Second People's Hospital), 454000, Jiaozuo, China.
Dan XueDepartment of Ultrasound Medicine, The First Affiliated Hospital of Henan Polytechnic University (Jiaozuo Second People's Hospital), 454000, Jiaozuo, China.
Xue-Hong ZhouDepartment of Endocrinology, The First Affiliated Hospital of Henan Polytechnic University (Jiaozuo Second People's Hospital), 454000, Jiaozuo, China. m18639186869@163.com.
Henan Polytechnic University · CN

Funding

Jiaozuo City Medical Research Project 2017KY040
6 · The paper itself

Abstract

purposeTo compare the effects and safety of using microwave ablation (MWA) and surgical resection for the treatment of benign thyroid nodules (BTNs) under ultrasonic guidance and investigate the effects of this treatment on stress response.

methodsPatients with BTNs were divided into the MWA and operation groups (72 cases each). Interleukin (IL)-6, IL-8, serum tumor necrosis factor (TNF-α), and hydrostatic visual analog scale (VAS) prior to the operation, at 6 h, 24 h, and 72 h post-operation were compared between the two groups. Operation times, hospitalization times, hospitalization expenses, and postoperative complications in the two groups were also compared. All patients underwent routine ultrasound and thyroid function testing at 3 and 6 months post-operation for assessment of nodule changes and thyroid hormone levels.

resultsCompared to the MWA group, the operation group had longer average operation times, longer hospital stays, a higher rate of neck pain after surgery, and a higher rate of fever (P < 0.05). Body temperature, as well as VAS, IL-6, IL-8, and TNF-α levels in the operation group were higher than those in the MWA group at 6 h, 24 h, and 72 h post-operation (P < 0.05). The levels of free thyroxine and free triiodothyronine in the operation group were lower than those in the MWA group (P < 0.05).

conclusionMWA is a safe and effective treatment for patients with BTNs. The effects of MWA are more tolerable than those of surgical resection and the physiological function of the thyroid is preserved, which has high clinical value.

Indexed as

Radiofrequency AblationThyroidectomyAdultCase-Control StudiesCytokinesFemaleHumansMaleMicrowavesMiddle AgedOperative TimePostoperative PeriodRetrospective StudiesStress, PhysiologicalThyroid Function TestsThyroid NoduleCytokinesBenign nodulesClinical effectMicrowave ablationStress responseThyroid

Identifiers

PMID30904997
OpenAlexW2923377614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.