Evidence map›Paper›PMID 30904044›Full record

ArticleThe American journal of the medical sciences2019

Impact of Cirrhosis on Pneumonia-Related Outcomes in Hospitalized Older Veterans.

Zachary Boivin, Mario F Perez, Nkiruka C Atuegwu, Antonio Anzueto, Eric M Mortensen

Abstract read
In one paragraph

Article in The American journal of the medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zachary BoivinUConn Health, University of Connecticut School of Medicine, Farmington, Connecticut.
Mario F PerezUConn Health, University of Connecticut School of Medicine, Farmington, Connecticut.
Nkiruka C AtuegwuUConn Health, University of Connecticut School of Medicine, Farmington, Connecticut.
Antonio AnzuetoUniversity of Texas Health Science Center at San Antonio, San Antonio, Texas; South Texas Veterans Health Care System, San Antonio, Texas.
Eric M MortensenUConn Health, University of Connecticut School of Medicine, Farmington, Connecticut; VA North Texas Health Care System, Dallas, Texas. Electronic address: mortensen@uchc.edu.
UConn Health · USThe University of Texas Health Science Center at San Antonio · US

Funding

Impact of statins and ACE inhibitors on outcomes for pneumonia and sepsisR01NR010828 · NINR · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI MORTENSEN, ERIC M. · 2007 to 2009
$947k
NINR NIH HHS R01 NR010828
6 · The paper itself

Abstract

backgroundPrior research has demonstrated high mortality rates in patients with cirrhosis who contract bacterial infections. The purpose of our study was to explore clinical outcomes such as 90-day mortality, rehospitalization, and intensive care unit (ICU) admission in older veterans with pneumonia and cirrhosis.

methodsWe conducted a retrospective cohort study of hospitalized patients with community-acquired pneumonia at any Departments of Veterans Affairs (VA) hospital over a 10-year period. We included patients 65 years or older who consistently received VA care and who were diagnosed with community-acquired pneumonia. There were 103,997 patients who met the inclusion criteria, and 1,246 patients with cirrhosis. We used multilevel regression models to examine the association between cirrhosis and the outcomes of interest after controlling for potential confounders.

resultsCirrhosis was associated with significantly increased odds of 90-day mortality (odds ratio 1.79, 95% confidence interval, 1.57-2.04). There were also significantly increased odds of rehospitalization within 90-days (1.30, 1.16-1.47). No significant association was found with ICU admission (1.00, 0.83-1.19).

conclusionsWe found an association between cirrhosis and 90-day mortality and rehospitalization in older patients with pneumonia. We suggest that physicians should carefully monitor patients with cirrhosis who develop pneumonia.

Indexed as

AgedAged, 80 and overCohort StudiesCommunity-Acquired InfectionsHospitalizationHospitals, VeteransHumansLiver CirrhosisMalePneumoniaRetrospective StudiesRisk FactorsUnited StatesVeteransCirrhosisMortalityPneumoniaRehospitalization

Identifiers

PMID30904044
PMCPMC6863737
OpenAlexW2910669420

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.