Evidence map›Paper›PMID 30903733›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2019

The changing landscape of live kidney donation in the United States from 2005 to 2017.

Fawaz Al Ammary, Mary Grace Bowring, Allan B Massie, Sile Yu, Madeleine M Waldram, Jacqueline Garonzik-Wang, Alvin G Thomas, Courtenay M Holscher, Mohamud A Qadi, Macey L Henderson and 5 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07206069 (Telemedicine for Evaluation and Counseling of Living Kidney Donor Candidates), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07206069 narecruitingnot on this mapstarted 2026, after this paper: background citation

Telemedicine for Evaluation and Counseling of Living Kidney Donor Candidates

TypeinterventionalSponsorUniversity of California, IrvineRan2026 to 2026Enrolled70ConditionsHealthy, Living Kidney DonationArmsStandard Care (in control arm), Telemedicine Shared Decision-Making
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Examining post-donation outcomes in Hispanic/Latinx living kidney donors in the United States: A systematic review.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
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  11. Telemedicine services for living kidney donation: A US survey of multidisciplinary providers.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  12. Review
  13. Article
  14. Article
  15. The first increase in live kidney donation in the United States in 15 years.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Early graft losses in paired kidney exchange: Experience from 10 years of the National Kidney Registry.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Fawaz Al AmmaryDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0003-0928-2860
Mary Grace BowringDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-7299-7730
Allan B MassieDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Sile YuDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Madeleine M WaldramDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Jacqueline Garonzik-WangDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Alvin G ThomasDepartment of Epidemiology, University of North Carolina, Chapel Hill, North Carolina.ORCID 0000-0003-4911-8192
Courtenay M HolscherDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-5808-5954
Mohamud A QadiDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Macey L HendersonDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-4239-1252
Alexander C WisemanDepartment of Medicine, University of Colorado School of Medicine, Aurora, Colorado.
Jane GrallaDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado.
Daniel C BrennanDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Dorry L SegevDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Abimereki D MuzaaleDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-3287-6061
Johns Hopkins University · USUniversity of Colorado Denver · USNational Marrow Donor Program · USUniversity of North Carolina at Chapel Hill · US

Funding

Cardiovascular Epidemiology Training GrantT32HL007055 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Wayne D. Rosamond · 1986 to 2026
$10.0M
Patient Oriented Research in Solid Organ TransplantationK24AI144954 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SEGEV, DORRY L. · 2020 to 2024
$956k
Patient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922k
Determinants of chronic kidney disease in African-American live kidney donorsK01DK101677 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI MASSIE, ALLAN B · 2015 to 2019
$789k
Technological Innovations for Live Kidney Donor Follow-up Care ManagementK01DK114388 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LEVAN, MACEY LEIGH · 2017 to 2021
$720k
Aggressive Center Report Cards to Safely Increase Transplantation of Suboptimal KidneysK23DK115908 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI GARONZIK WANG, JACQUELINE M · 2018 to 2021
$516k
NHLBI NIH HHS T32 HL007055NIAID NIH HHS K24 AI144954NIDDK NIH HHS K01 DK101677NIDDK NIH HHS K01 DK114388NIDDK NIH HHS K23 DK115908NIDDK NIH HHS K24 DK101828
6 · The paper itself

Abstract

The number of live kidney donors has declined since 2005. This decline parallels the evolving knowledge of risk for biologically related, black, and younger donors. To responsibly promote donation, we sought to identify declining low-risk donor subgroups that might serve as targets for future interventions. We analyzed a national registry of 77 427 donors and quantified the change in number of donors per 5-year increment from 2005 to 2017 using Poisson regression stratified by donor-recipient relationship and race/ethnicity. Among related donors aged <35, 35 to 49, and ≥50 years, white donors declined by 21%, 29%, and 3%; black donors declined by 30%, 31%, and 12%; Hispanic donors aged <35 and 35 to 49 years declined by 18% and 15%, and those aged ≥50 increased by 10%. Conversely, among unrelated donors aged <35, 35 to 49, and ≥50 years, white donors increased by 12%, 4%, and 24%; black donors aged <35 and 35 to 49 years did not change but those aged ≥50 years increased by 34%; Hispanic donors increased by 16%, 21%, and 46%. Unlike unrelated donors, related donors were less likely to donate in recent years across race/ethnicity. Although this decline might be understandable for related younger donors, it is less understandable for lower-risk related older donors (≥50 years). Biologically related older individuals are potential targets for interventions to promote donation.

Indexed as

Living DonorsAdultFemaleHumansKidney DiseasesKidney TransplantationMaleMiddle AgedOutcome Assessment, Health CarePoisson DistributionRegistriesRegression AnalysisRiskTissue and Organ HarvestingTissue and Organ ProcurementUnited Statesclinical research/practicedonor nephrectomydonors and donation: livingkidney transplantation: living donorkidney transplantation/nephrologyregistry/registry analysis

Identifiers

PMID30903733
PMCPMC6711793
OpenAlexW2942787186

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.