Evidence map›Paper›PMID 30903632›Full record

ArticleMagnetic resonance in medicine2019

NMR shutter-speed elucidates apparent population inversion of

Xin Li, Silvia Mangia, Jing-Huei Lee, Ruiliang Bai, Charles S Springer

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  6. Article
  7. Article
  8. Article
  9. DCE-MRI of Brain Fluid Barriers:Tissue barriers · 2022
    Article
  10. Article
  11. Gray matter blood-brain barrier water exchange dynamics are reduced in progressive multiple sclerosis.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2021
    Article
  12. Article
  13. Observation of Reduced Homeostatic Metabolic Activity and/or Coupling in White Matter Aging.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2020
    Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xin LiAdvanced Imaging Research Center, Oregon Health & Science University, Portland, Oregon.
Silvia MangiaCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota.
Jing-Huei LeeDepartment of Biomedical Engineering, University of Cincinnati, Cincinnati, Ohio.
Ruiliang BaiInterdisciplinary Institute of Neuroscience and Technology, Qiushi Academy for Advanced Studies, Key Laboratory of Biomedical Engineering of Ministry of Education, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, China.
Charles S SpringerAdvanced Imaging Research Center, Oregon Health & Science University, Portland, Oregon.

Funding

Institutional Career Development CoreKL2TR002492 · NCATS · UNIVERSITY OF MINNESOTA · PI INGBAR, DAVID H · 2018 to 2022
$6.3M
NCATS NIH HHS KL2 TR002492
6 · The paper itself

Abstract

purposeThe desire to quantitatively discriminate the extra- and intracellular tissue

methodsWe present a theoretical longitudinal relaxation analysis of considerable scope: it spans the low- and high-field situations.

resultsWe show the NMR shutter-speed organizing principle is pivotal in understanding how trans-membrane steady-state water exchange kinetics are manifest throughout the range. Our findings illuminate an aspect, apparent population inversion, which is crucial in understanding ultra-low field results.

conclusionsWithout an appreciation of apparent population inversion, significant misinterpretations of future data are likely. These could have unfortunate diagnostic consequences.

Indexed as

Cell MembraneMagnetic Resonance SpectroscopyModels, BiologicalSignal Processing, Computer-AssistedSodium-Potassium-Exchanging ATPaseWaterSodium-Potassium-Exchanging ATPaseWateractive water cyclingapparent population-inversionshutter-speed

Identifiers

PMID30903632
PMCPMC6593680

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.