ArticleEndocrine2019
Healthcare utilization and costs among patients with non-functioning pituitary adenomas.
Article in Endocrine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Factors Affecting Long-Term Outcomes and Quality of Life of Patients with Pituitary Adenoma After Endoscopic Endonasal Transsphenoidal Surgery (EETS) Using the SF-36 Questionnaire (Indonesian Version).Journal of the ASEAN Federation of Endocrine Societies · 2026Article
- Sex-related differences in healthcare utilization and costs among patients with pituitary adenomas.Pituitary · 2026Review
- Hospital frailty risk score predicts postoperative outcomes after endoscopic endonasal resection of non-functioning pituitary adenomas.Pituitary · 2025Article
- Healthcare utilization and costs among intracranial meningioma patients during long-term follow-up.Journal of neuro-oncology · 2023Article
- Costs and Its Determinants in Pituitary Tumour Surgery.Frontiers in endocrinology · 2022Article
- Healthcare utilization and costs among prolactinoma patients: a cross-sectional study and analysis of determinants.Pituitary · 2021Article
- SF-12 or SF-36 in pituitary disease? Toward concise and comprehensive patient-reported outcomes measurements.Endocrine · 2020Article
- Unmet needs and recommendations to improve meningioma care through patient, partner, and health care provider input: a mixed-method study.Neuro-oncology practice · 2020Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
purposeNon-functioning pituitary adenomas (NFPA) have a substantial impact on patients' health status, yet research on the extent of healthcare utilization and costs among these patients is scarce. The objective was to determine healthcare usage, associated costs, and their determinants among patients treated for an NFPA.
methodsIn a cross-sectional study, 167 patients treated for an NFPA completed four validated questionnaires. Annual healthcare utilization and associated costs were assessed through the medical consumption questionnaire (MTA iMCQ). In addition, the Leiden Bother and Needs Questionnaire for pituitary patients (LBNQ-Pituitary), Short Form-36 (SF-36), and EuroQol (EQ-5D) were administered. Furthermore, age, sex, endocrine status, treatment, and duration of follow-up were extracted from the medical records. Associations were analyzed using logistic/linear regression.
resultsAnnual healthcare utilization included: consultation of an endocrinologist (95% of patients), neurosurgeon (14%), and/or ophthalmologist (58%). Fourteen percent of patients had ≥1 hospitalization(s) and 11% ≥1 emergency room visit(s). Mean overall annual healthcare costs were € 3040 (SD 6498), highest expenditures included medication (31%), inpatient care (28%), and specialist care (17%). Factors associated with higher healthcare utilization and costs were greater self-perceived disease bother and need for support, worse mental and physical health status, younger age, and living alone.
conclusionHealthcare usage and costs among patients treated for an NFPA are substantial and were associated with self-perceived health status, disease bother, and healthcare needs rather than endocrine status, treatment, or duration of follow-up. These findings suggest that targeted interventions addressing disease bother and unmet needs in the chronic phase are needed.
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