ArticleEuropean journal of nutrition2020
Polyphenol intake and metabolic syndrome risk in European adolescents: the HELENA study.
Article in European journal of nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Dietary polyphenols and the risk of metabolic syndrome: a systematic review and meta-analysis.BMC endocrine disorders · 2024Pooled it
- [Research progress on dietary and exercise intervention for the prevention and treatment of non-alcoholic fatty liver disease in obese children].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025Review
- Article
- Five Underutilized Ecuadorian Fruits and Their Bioactive Potential as Functional Foods and in Metabolic Syndrome: A Review.Molecules (Basel, Switzerland) · 2024Review
- Dietary polyphenol intake, body composition and components of metabolic syndrome in a sample overweight and obese adults: a cross-sectional study.BMC endocrine disorders · 2023Article
- The relation between dietary phytochemical index and metabolic health status in overweight and obese adolescents.Scientific reports · 2023Article
- Total urinary polyphenols and ideal cardiovascular health metrics in Spanish adolescents enrolled in the SI Program: a cross-sectional study.Scientific reports · 2022Article
- Flavonoid Intake From Cocoa-Based Products and Adiposity Parameters in Adolescents in Spain.Frontiers in nutrition · 2022Article
- Grape polyphenols decrease circulating branched chain amino acids in overfed adults.Frontiers in nutrition · 2022Article
- The Association of Dietary Phytochemical Index with Metabolic Syndrome in Adults.Clinical nutrition research · 2021Article
- Identification of Nutritional Targets in Spanish Children Belonging to the LAyDI Cohort for the Development of Health Promotion Strategies in the First Two Years of Life.International journal of environmental research and public health · 2021Article
- Polyphenols in Urine and Cardiovascular Risk Factors: A Cross-Sectional Analysis Reveals Gender Differences in Spanish Adolescents from the SI! Program.Antioxidants (Basel, Switzerland) · 2020Article
- Inflammation in Obesity-Related Complications in Children: The Protective Effect of Diet and Its Potential Role as a Therapeutic Agent.Biomolecules · 2020Review
- Poor Dietary Polyphenol Intake in Childhood Cancer Patients.Nutrients · 2019Article
- Diet and Oxidative Status. The Dietary Pattern and Urinary 8-Isoprostane in Healthy Spanish Women.Antioxidants (Basel, Switzerland) · 2019Article
- Dietary Polyphenol Intake, Blood Pressure, and Hypertension: A Systematic Review and Meta-Analysis of Observational Studies.Antioxidants (Basel, Switzerland) · 2019Review
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Authors and funding
17 authors at 12 institutions in 10 countries.
Funding
Abstract
purposeThe role of polyphenol intake during adolescence to prevent metabolic syndrome (MetS) is little explored. This study aimed to evaluate the association between intake of total polyphenols, polyphenol classes and the 10 most consumed individual polyphenols with MetS risk in European adolescents.
methodsOf the cross-sectional HELENA study, 657 adolescents (54% girls; 14.8% overweight; 12.5-17.5 year) had a fasting blood sample and polyphenol intake data from two non-consecutive 24-h recalls matched with the Phenol-Explorer database. MetS was defined via the pediatric American Heart Association definition. Multilevel linear regressions examined the associations of polyphenol quartiles with MetS components, while logistic regression examined the associations with MetS risk.
resultsAfter adjusting for all potential confounders (socio-demographics and nine nutrients), total polyphenol intake, polyphenol classes and individual polyphenols were not associated with MetS risk. From all MetS components, only BMI z-score was modestly inversely associated with total polyphenol intake. Further sub analyses on polyphenol classes revealed that flavonoid intake was significantly associated with higher diastolic blood pressure and lower BMI, and phenolic acid intake was associated with higher low-density cholesterol. For individual polyphenols, the above BMI findings were often confirmed (not independent from dietary intake) and a few associations were found with insulin resistance.
conclusionHigher intakes of total polyphenols and flavonoids were inversely associated with BMI. No consistent associations were found for other MetS components.
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