Evidence map›Paper›PMID 30903337›Full record

ArticleEuropean radiology2019

Multi-detector CT imaging: impact of virtual tube current reduction and sparse sampling on detection of vertebral fractures.

Nico Sollmann, Kai Mei, Dennis M Hedderich, Christian Maegerlein, Felix K Kopp, Maximilian T Löffler, Claus Zimmer, Ernst J Rummeny, Jan S Kirschke, Thomas Baum and 1 more

Open access · hybridAbstract read
In one paragraph

Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Simulated low-dose multi-detector computed tomography: spatial effects on surrogate parameters of bone strength at the proximal femur.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
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  12. Epidemiology and reporting of osteoporotic vertebral fractures in patients with long-term hospital records based on routine clinical CT imaging.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Nico SollmannDepartment of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany. Nico.Sollmann@tum.de.ORCID http://orcid.org/0000-0002-8120-2223
Kai MeiDepartment of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675 Munich, Germany.
Dennis M HedderichDepartment of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
Christian MaegerleinDepartment of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
Felix K KoppDepartment of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675 Munich, Germany.
Maximilian T LöfflerDepartment of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
Claus ZimmerDepartment of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
Ernst J RummenyDepartment of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675 Munich, Germany.
Jan S KirschkeDepartment of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
Thomas BaumDepartment of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
Peter B NoëlDepartment of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675 Munich, Germany.
TUM Klinikum · DE

Funding

Bundesministerium f?r Bildung und Forschung IMEDO (13GW0072C)Deutsche Forschungsgemeinschaft Research Training Group GRK 2274H2020 European Research Council No 637164 ? iBack ? ERC-2014-STG
6 · The paper itself

Abstract

purposeTo systematically evaluate the effects of virtual tube current reduction and sparse sampling on image quality and vertebral fracture diagnostics in multi-detector computed tomography (MDCT). MATERIALS AND

methodsIn routine MDCT scans of 35 patients (80.0% females, 70.6 ± 14.2 years, 65.7% showing vertebral fractures), reduced radiation doses were retrospectively simulated by virtually lowering tube currents and applying sparse sampling, considering 50%, 25%, and 10% of the original tube current and projections, respectively. Two readers evaluated items of image quality and presence of vertebral fractures. Readout between the evaluations in the original images and those with virtually lowered tube currents or sparse sampling were compared.

resultsA significant difference was revealed between the evaluations of image quality between MDCT with virtually lowered tube current and sparse-sampled MDCT (p < 0.001). Sparse-sampled data with only 25% of original projections still showed good to very good overall image quality and contrast of vertebrae as well as minimal artifacts. There were no missed fractures in sparse-sampled MDCT with 50% reduction of projections, and clinically acceptable determination of fracture age was possible in MDCT with 75% reduction of projections, in contrast to MDCT with 50% or 75% virtual tube current reduction, respectively.

conclusionSparse-sampled MDCT provides adequate image quality and diagnostic accuracy for vertebral fracture detection with 50% of original projections in contrast to corresponding MDCT with lowered tube current. Thus, sparse sampling is a promising technique for dose reductions in MDCT that could be introduced in future generations of scanners. KEY POINTS: • MDCT with a reduction of projection numbers of 50% still showed high diagnostic accuracy without any missed vertebral fractures. • Clinically acceptable determination of vertebral fracture age was possible in MDCT with a reduction of projection numbers of 75%. • With sparse sampling, higher reductions in radiation exposure can be achieved without compromised image or diagnostic quality in routine MDCT of the spine as compared to MDCT with reduced tube currents.

Indexed as

ArtifactsAdultAgedAged, 80 and overCervical VertebraeFemaleHumansMaleMiddle AgedMultidetector Computed TomographyRetrospective StudiesSpinal FracturesThoracic VertebraeBone fracturesMulti-detector computed tomographyOsteoporosisRadiation exposureSpine

Identifiers

PMID30903337
PMCPMC6554251
OpenAlexW2922875143

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.