ArticleAnnals of surgical oncology2019
Differences in Esophageal Cancer Surgery in Terms of Surgical Approach and Extent of Lymphadenectomy: Findings of an International Survey.
Article in Annals of surgical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- [Modern concepts in the surgical treatment of esophageal cancer].Chirurgie (Heidelberg, Germany) · 2026Review
- Teaching to the Standard: The Cancer Surgery Standards Program as a Framework for Surgical Oncology Training.Annals of surgical oncology · 2026Article
- Optimizing perioperative care in esophagectomy: a narrative review.Journal of thoracic disease · 2026Review
- Sentinel Lymph Node Mapping in Esophageal Cancer: Many Routes to an Elusive Destination.Annals of surgical oncology · 2026Article
- Perioperative outcomes and survival of indocyanine green-guided minimally esophagectomy in patients with esophageal cancer: a retrospective comparison study.Quantitative imaging in medicine and surgery · 2026Article
- Sentinel Lymph Node Mapping in Esophageal Cancer: Current Status and Future Directions.Annals of surgical oncology · 2025Review
- Deep learning-based prediction of enhanced CT scans for lymph node metastasis in esophageal squamous cell carcinoma.Japanese journal of radiology · 2025Article
- The Impact of Paratracheal Lymphadenectomy on Survival After Esophagectomy: A Nationwide Propensity Score Matched Analysis.Cancers · 2025Article
- History and evidence for state of the art of lymphadenectomy in esophageal cancer surgery.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024Review
- The impact of hospital experience in bariatric surgery on short-term outcomes after minimally invasive esophagectomy: a nationwide analysis.Surgical endoscopy · 2024Article
- Predicting mortality in patients with anastomotic leak after esophagectomy: development of a prediction model using data from the TENTACLE-Esophagus study.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023Article
- Role of Lower Esophageal Squamous Cell Carcinoma Margin Location on Abdominal Lymph Node Metastasis Risk.Journal of clinical medicine · 2023Article
- Clinical implications of chyle leakage following esophagectomy.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023Article
- Symptom clusters and impact on quality of life in esophageal cancer patients.Health and quality of life outcomes · 2022Article
- Today's Mistakes and Tomorrow's Wisdom in the Surgical Treatment of Barrett's Adenocarcinoma.Visceral medicine · 2022Review
- Esophageal cancer with a double aortic arch: a case report and literature review.Journal of cardiothoracic surgery · 2022Review
- Peri-operative approach to esophagectomy: a narrative review from the anesthesiological standpoint.Journal of thoracic disease · 2021Review
- Textbook outcome for esophageal cancer surgery: an international consensus-based update of a quality measure.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2021Article
- Transition from open to minimally invasive en bloc esophagectomy can be achieved without compromising surgical quality.Surgical endoscopy · 2021Article
- High-quality nursing can reduce the incidence of adverse events in esophageal cancer patients after operation in the intensive care unit and improve postoperative rehabilitation.American journal of translational research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEsophagectomy and lymphadenectomy are essential parts of the multimodal treatment of esophageal carcinoma with curative intent. Treatment regimens vary globally and are subject to debate. A global survey was designed to gain insight into current practice.
methodsFifty-seven international expert upper gastrointestinal surgeons received a personal invitation to participate in the survey, which focused on demographics and experience; extent of lymphadenectomy in adeno and squamous cell carcinoma; use of classification systems; neoadjuvant therapy; surgical approach; and specimen handling.
resultsThe response rate was 88% (50/57 surgeons), with a mean age of 51.6 years and a median number of 15 years of experience in esophageal surgery. The variety in the extent of lymphadenectomy in proximal, middle and distal squamous cell carcinoma, and Siewert I, II and III adenocarcinoma, was considerable. The number of different combinations of lymph node (LN) stations that were resected in the same tumor was high, while the number of surgeons who removed the exact same combination of LN stations was low. Illustrative is Siewert I adenocarcinoma, in which 27 unique combinations of LN stations were resected, with a maximum of two surgeons performing the exact same dissection. Use of neoadjuvant therapy, surgical approach, and specimen handling also show great variety among participants.
conclusionThere is no uniform, worldwide strategy for surgical treatment of esophageal cancer. The extent of lymphadenectomy shows great variation for both histologic types. An international observational study is needed to provide evidence on the distribution pattern of lymph node metastases in esophageal cancer and the necessary extent of lymphadenectomy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.