Evidence map›Paper›PMID 30903237›Full record

ArticleSocial psychiatry and psychiatric epidemiology2019

Demographic and diagnostic profiles of older people with intellectual disability and prescription of antipsychotics.

Anna Axmon, Gerd Ahlström, Rebecca Gagnemo Persson, Jonas Eberhard

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Psychotropic drugs intake in people aging with intellectual disability: Prevalence and predictors.Journal of applied research in intellectual disabilities : JARID · 2022
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anna AxmonEPI@LUND, Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 221 80, Lund, Sweden. anna.axmon@med.lu.se.ORCID http://orcid.org/0000-0002-4539-8337
Gerd AhlströmDepartment of Health Sciences, Faculty of Medicine, Lund University, 221 00, Lund, Sweden.ORCID http://orcid.org/0000-0001-6230-7583
Rebecca Gagnemo PerssonDepartment of Health Sciences, Faculty of Medicine, Lund University, 221 00, Lund, Sweden.ORCID http://orcid.org/0000-0003-2874-6712
Jonas EberhardDivision of Psychiatry, Department of Clinical Sciences Lund, Lund University, 251 87, Helsingborg, Sweden.ORCID http://orcid.org/0000-0003-0364-2626
Lund University · SE

Funding

Forskningsrådet om Hälsa, Arbetsliv och Välfärd 2014-4753
6 · The paper itself

Abstract

purposeTo describe demographic and diagnostic profiles in a national cohort of older people with intellectual disability (ID) who were prescribed antipsychotics.

methodsUsing national registers, we identified people with ID who were 55 + years in 2012 (n = 7936), as well as a subcohort with complete information on demographic factors (sex, year of birth, severity of ID, presence of behavior impairment, and residence in special housing; n = 1151). Data regarding diagnoses and prescription of antipsychotics were added for the time period 2006-2012. The potential effects of demographic factors and diagnoses on the prescription of sedating and less-sedating antipsychotics, respectively, were assessed in separate models by estimating the relative risks (RRs) of prescription.

resultsOf the demographic factors, severe/profound ID (RR 1.17), behavior impairment (RR 1.34), and living in special housing (RR 1.25) were associated with prescription of sedating antipsychotics, whereas only behavior impairment (RR 1.42) was associated with prescription of less-sedating antipsychotics. For both sedating and less-sedating antipsychotics, the diagnoses with the largest association (i.e., highest relative risk) were schizophrenia (RR 2.17 for sedating and RR 1.81 for less-sedating) and ID (RR 1.84 and RR 1.68, respectively), followed by disorders of psychological development (for sedating antipsychotics, RR 1.57) and organic mental disorders (for less-sedating antipsychotics, RR 1.55).

conclusionsThe associations between prescription of antipsychotics and demographic factors and non-psychotic diagnoses, respectively, suggest that older people with ID may be prescribed antipsychotic medication without thorough psychiatric diagnosing. If so, there is a need for improving the abilities of health care professionals to properly diagnose and manage psychiatric illness in this population.

Indexed as

AgedAged, 80 and overAntipsychotic AgentsCohort StudiesDemographyDrug PrescriptionsFemaleHousingHumansInappropriate PrescribingIntellectual DisabilityMaleMiddle AgedNeurocognitive DisordersRegistriesSchizophreniaAntipsychotic AgentsAgingChallenging behaviorComorbiditiesDrug prescriptionMental retardationSchizophrenia

Identifiers

PMID30903237
OpenAlexW2923432112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.