ArticleGenome biology and evolution2019
Carbon Fixation by Marine Ultrasmall Prokaryotes.
Article in Genome biology and evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- The Elusive Fraction of Marine Plankton Diversity: Size, Abundance and Taxonomic Composition of 0.2 μm-Filterable Prokaryotes Across Three Contrasting Coastal Environments.Molecular ecology · 2026Article
- Induced pathogenicity toward open-ocean diatoms by a filterable bacterium Ekhidna algicida sp. nov.The ISME journal · 2026Article
- Diverse Patescibacteria assemblages and prevalence of ultra-small free-living Parcubacteria along a subterranean estuary.mSystems · 2025Article
- Viruses are a key regulator of the microbial carbon cycle in the deep-sea biosphere.Environmental science and ecotechnology · 2025Article
- Identification of Key Features Pivotal to the Characteristics and Functions of Gut Bacteria Taxa through Machine Learning Methods.Current gene therapy · 2025Article
- Development and validation of an experimental life support system to study coral reef microbial communities.Scientific reports · 2024Article
- Cross-biome microbial networks reveal functional redundancy and suggest genome reduction through functional complementarity.Communications biology · 2024Article
- Community Composition and Functional Characterization of Microorganisms in Surface Sediment of the New Britain Trench.Current microbiology · 2024Article
- Distribution and survival strategies of endemic and cosmopolitan diazotrophs in the Arctic Ocean.The ISME journal · 2023Article
- Genome-resolved metagenomic analysis of Great Amazon Reef System sponge-associated Latescibacterota bacteria and their potential contributions to the host sponge and reef.Frontiers in microbiomes · 2023Article
- Widespread but Poorly Understood Bacteria: Candidate Phyla Radiation.Microorganisms · 2022Review
- Article
- Global distribution patterns of marine nitrogen-fixers by imaging and molecular methods.Nature communications · 2021Article
- Article
- Cell Plasticity and Genomic Structure of a Novel FilterableMicroorganisms · 2020Article
- Femtoplankton: What's New?Viruses · 2020Review
- Article
- Size Matters: Ultra-small and Filterable Microorganisms in the Environment.Microbes and environments · 2020Review
- Highlight: Contribution of Ultra-Small Microbes to Global Carbon Cycles.Genome biology and evolution · 2019Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autotrophic carbon fixation is a crucial process for sustaining life on Earth. To date, six pathways, the Calvin-Benson-Bassham cycle, the reductive tricarboxylic acid cycle, the 3-hydroxypropionate bi-cycle, the Wood-Ljungdahl pathway, the dicarboxylate/4-hydroxybutyrate cycle, and the 4-hydroxybutyrate cycle, have been described. Nano-organisms such as members of the Candidate Phyla Radiation (CPR) bacterial superphylum and the Diapherotrites, Parvarchaeota, Aenigmarchaeota, Nanoarchaeota, Nanohalorchaeota (DPANN) archaeal superphylum could deeply impact carbon cycling and carbon fixation in ways that are still to be determined. CPR and DPANN are ubiquitous in the environment but understudied; their gene contents are not exhaustively described; and their metabolisms are not yet fully understood. Here, the completeness of each of the above pathways was quantified and tested for the presence of all key enzymes in nano-organisms from across the World Ocean. The novel marine ultrasmall prokaryotes were demonstrated to collectively harbor the genes required for carbon fixation, in particular the "energetically efficient" dicarboxylate/4-hydroxybutyrate pathway and the 4-hydroxybutyrate pathway. This contrasted with the known carbon metabolic pathways associated with CPR members in aquifers, where they are described as degraders (Castelle CJ, et al. 2015. Genomic expansion of domain archaea highlights roles for organisms from new phyla in anaerobic carbon cycling. Curr Biol. 25(6):690-701; Castelle CJ, et al. 2018. Biosynthetic capacity, metabolic variety and unusual biology in the CPR and DPANN radiations. Nat Rev Microbiol. 16(10):629-645; Anantharaman K, et al. 2016. Thousands of microbial genomes shed light on interconnected biogeochemical processes in an aquifer system. Nat Commun. 7:13219.). Our findings suggest that nano-organisms have a broader contribution to carbon fixation and cycling than currently assumed. Furthermore, CPR and DPANN superphyla are possibly not the only nanosized prokaryotes; therefore, the discovery of new autotrophic marine nano-organisms by future single cell genomics is anticipated.
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