Evidence map›Paper›PMID 30902908›Full record

Trial reportNeurology2019

Randomized trial of care management to improve Parkinson disease care quality.

Karen I Connor, Eric M Cheng, Frances Barry, Hilary C Siebens, Martin L Lee, David A Ganz, Brian S Mittman, Megan K Connor, Lisa K Edwards, Michael G McGowan and 1 more

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01532986 (Improving Quality of Care in Parkinson's Disease), which is not on this map. Cited by 30 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 5 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01532986 nacompletednot on this map

Improving Quality of Care in Parkinson's Disease: A Randomized Controlled Trial

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2012 to 2017Enrolled345ConditionsParkinson DiseaseArmsCoordinated care management for Parkinson's disease, Educational handout
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 5 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Person-centred integrated care for people living with Parkinson's, Huntington's and Multiple Sclerosis: A systematic review.Health expectations : an international journal of public participation in health care and health policy · 2024
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Article
  11. Review
  12. Review
  13. The Treatment of Older Patients with Parkinson's Disease.Deutsches Arzteblatt international · 2025
    Review
  14. Article
  15. Article
  16. Breaking barriers in Parkinson's care: the multidisciplinary team approach.Journal of neural transmission (Vienna, Austria : 1996) · 2024
    Review
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Karen I ConnorFrom the Veterans Affairs Greater Los Angeles Parkinson's Disease Research, Education and Clinical Center (K.I.C., L.K.E., M.G.M.); University of California Los Angeles David Geffen School of Medicine (K.I.C., E.M.C., F.B.); Siebens Patient Care Communications LLC (H.C.S.), Seal Beach; Veterans Affairs Sepulveda Ambulatory Care Center (M.L.L.), North Hills; University of California Los Angeles Fielding School of Public Health (M.L.L.); Veterans Affairs Geriatric Research, Education and Clinical Center and Center for the Study of Healthcare Innovation, Implementation and Policy (D.A.G.), Los Angeles; Kaiser Permanente Research (B.S.M.), Pasadena; University of California San Francisco (M.K.C.); and Icahn School of Medicine at Mount Sinai (B.G.V.), New York, NY. kiconnor@ucla.edu.
Eric M ChengFrom the Veterans Affairs Greater Los Angeles Parkinson's Disease Research, Education and Clinical Center (K.I.C., L.K.E., M.G.M.); University of California Los Angeles David Geffen School of Medicine (K.I.C., E.M.C., F.B.); Siebens Patient Care Communications LLC (H.C.S.), Seal Beach; Veterans Affairs Sepulveda Ambulatory Care Center (M.L.L.), North Hills; University of California Los Angeles Fielding School of Public Health (M.L.L.); Veterans Affairs Geriatric Research, Education and Clinical Center and Center for the Study of Healthcare Innovation, Implementation and Policy (D.A.G.), Los Angeles; Kaiser Permanente Research (B.S.M.), Pasadena; University of California San Francisco (M.K.C.); and Icahn School of Medicine at Mount Sinai (B.G.V.), New York, NY.
Frances BarryFrom the Veterans Affairs Greater Los Angeles Parkinson's Disease Research, Education and Clinical Center (K.I.C., L.K.E., M.G.M.); University of California Los Angeles David Geffen School of Medicine (K.I.C., E.M.C., F.B.); Siebens Patient Care Communications LLC (H.C.S.), Seal Beach; Veterans Affairs Sepulveda Ambulatory Care Center (M.L.L.), North Hills; University of California Los Angeles Fielding School of Public Health (M.L.L.); Veterans Affairs Geriatric Research, Education and Clinical Center and Center for the Study of Healthcare Innovation, Implementation and Policy (D.A.G.), Los Angeles; Kaiser Permanente Research (B.S.M.), Pasadena; University of California San Francisco (M.K.C.); and Icahn School of Medicine at Mount Sinai (B.G.V.), New York, NY.
Hilary C SiebensFrom the Veterans Affairs Greater Los Angeles Parkinson's Disease Research, Education and Clinical Center (K.I.C., L.K.E., M.G.M.); University of California Los Angeles David Geffen School of Medicine (K.I.C., E.M.C., F.B.); Siebens Patient Care Communications LLC (H.C.S.), Seal Beach; Veterans Affairs Sepulveda Ambulatory Care Center (M.L.L.), North Hills; University of California Los Angeles Fielding School of Public Health (M.L.L.); Veterans Affairs Geriatric Research, Education and Clinical Center and Center for the Study of Healthcare Innovation, Implementation and Policy (D.A.G.), Los Angeles; Kaiser Permanente Research (B.S.M.), Pasadena; University of California San Francisco (M.K.C.); and Icahn School of Medicine at Mount Sinai (B.G.V.), New York, NY.
Martin L LeeFrom the Veterans Affairs Greater Los Angeles Parkinson's Disease Research, Education and Clinical Center (K.I.C., L.K.E., M.G.M.); University of California Los Angeles David Geffen School of Medicine (K.I.C., E.M.C., F.B.); Siebens Patient Care Communications LLC (H.C.S.), Seal Beach; Veterans Affairs Sepulveda Ambulatory Care Center (M.L.L.), North Hills; University of California Los Angeles Fielding School of Public Health (M.L.L.); Veterans Affairs Geriatric Research, Education and Clinical Center and Center for the Study of Healthcare Innovation, Implementation and Policy (D.A.G.), Los Angeles; Kaiser Permanente Research (B.S.M.), Pasadena; University of California San Francisco (M.K.C.); and Icahn School of Medicine at Mount Sinai (B.G.V.), New York, NY.
David A GanzFrom the Veterans Affairs Greater Los Angeles Parkinson's Disease Research, Education and Clinical Center (K.I.C., L.K.E., M.G.M.); University of California Los Angeles David Geffen School of Medicine (K.I.C., E.M.C., F.B.); Siebens Patient Care Communications LLC (H.C.S.), Seal Beach; Veterans Affairs Sepulveda Ambulatory Care Center (M.L.L.), North Hills; University of California Los Angeles Fielding School of Public Health (M.L.L.); Veterans Affairs Geriatric Research, Education and Clinical Center and Center for the Study of Healthcare Innovation, Implementation and Policy (D.A.G.), Los Angeles; Kaiser Permanente Research (B.S.M.), Pasadena; University of California San Francisco (M.K.C.); and Icahn School of Medicine at Mount Sinai (B.G.V.), New York, NY.
Brian S MittmanFrom the Veterans Affairs Greater Los Angeles Parkinson's Disease Research, Education and Clinical Center (K.I.C., L.K.E., M.G.M.); University of California Los Angeles David Geffen School of Medicine (K.I.C., E.M.C., F.B.); Siebens Patient Care Communications LLC (H.C.S.), Seal Beach; Veterans Affairs Sepulveda Ambulatory Care Center (M.L.L.), North Hills; University of California Los Angeles Fielding School of Public Health (M.L.L.); Veterans Affairs Geriatric Research, Education and Clinical Center and Center for the Study of Healthcare Innovation, Implementation and Policy (D.A.G.), Los Angeles; Kaiser Permanente Research (B.S.M.), Pasadena; University of California San Francisco (M.K.C.); and Icahn School of Medicine at Mount Sinai (B.G.V.), New York, NY.
Megan K ConnorFrom the Veterans Affairs Greater Los Angeles Parkinson's Disease Research, Education and Clinical Center (K.I.C., L.K.E., M.G.M.); University of California Los Angeles David Geffen School of Medicine (K.I.C., E.M.C., F.B.); Siebens Patient Care Communications LLC (H.C.S.), Seal Beach; Veterans Affairs Sepulveda Ambulatory Care Center (M.L.L.), North Hills; University of California Los Angeles Fielding School of Public Health (M.L.L.); Veterans Affairs Geriatric Research, Education and Clinical Center and Center for the Study of Healthcare Innovation, Implementation and Policy (D.A.G.), Los Angeles; Kaiser Permanente Research (B.S.M.), Pasadena; University of California San Francisco (M.K.C.); and Icahn School of Medicine at Mount Sinai (B.G.V.), New York, NY.
Lisa K EdwardsFrom the Veterans Affairs Greater Los Angeles Parkinson's Disease Research, Education and Clinical Center (K.I.C., L.K.E., M.G.M.); University of California Los Angeles David Geffen School of Medicine (K.I.C., E.M.C., F.B.); Siebens Patient Care Communications LLC (H.C.S.), Seal Beach; Veterans Affairs Sepulveda Ambulatory Care Center (M.L.L.), North Hills; University of California Los Angeles Fielding School of Public Health (M.L.L.); Veterans Affairs Geriatric Research, Education and Clinical Center and Center for the Study of Healthcare Innovation, Implementation and Policy (D.A.G.), Los Angeles; Kaiser Permanente Research (B.S.M.), Pasadena; University of California San Francisco (M.K.C.); and Icahn School of Medicine at Mount Sinai (B.G.V.), New York, NY.
Michael G McGowanFrom the Veterans Affairs Greater Los Angeles Parkinson's Disease Research, Education and Clinical Center (K.I.C., L.K.E., M.G.M.); University of California Los Angeles David Geffen School of Medicine (K.I.C., E.M.C., F.B.); Siebens Patient Care Communications LLC (H.C.S.), Seal Beach; Veterans Affairs Sepulveda Ambulatory Care Center (M.L.L.), North Hills; University of California Los Angeles Fielding School of Public Health (M.L.L.); Veterans Affairs Geriatric Research, Education and Clinical Center and Center for the Study of Healthcare Innovation, Implementation and Policy (D.A.G.), Los Angeles; Kaiser Permanente Research (B.S.M.), Pasadena; University of California San Francisco (M.K.C.); and Icahn School of Medicine at Mount Sinai (B.G.V.), New York, NY.
Barbara G VickreyFrom the Veterans Affairs Greater Los Angeles Parkinson's Disease Research, Education and Clinical Center (K.I.C., L.K.E., M.G.M.); University of California Los Angeles David Geffen School of Medicine (K.I.C., E.M.C., F.B.); Siebens Patient Care Communications LLC (H.C.S.), Seal Beach; Veterans Affairs Sepulveda Ambulatory Care Center (M.L.L.), North Hills; University of California Los Angeles Fielding School of Public Health (M.L.L.); Veterans Affairs Geriatric Research, Education and Clinical Center and Center for the Study of Healthcare Innovation, Implementation and Policy (D.A.G.), Los Angeles; Kaiser Permanente Research (B.S.M.), Pasadena; University of California San Francisco (M.K.C.); and Icahn School of Medicine at Mount Sinai (B.G.V.), New York, NY.
Geriatric Research Education and Clinical Center · USCenter for the Study of Healthcare Provider Behavior · USOffice of Patient Care Services · USKaiser Permanente · USUniversity of California, San Francisco · USVA Sepulveda Ambulatory Care Center · US

Funding

HSRD VA I01 HX000651
6 · The paper itself

Abstract

objectiveTo test effects on care quality of Chronic Care Model-based Parkinson disease (PD) management.

methodsThis 2-group stratified randomized trial involved 328 veterans with PD in southwestern United States. Guided care management, led by PD nurses, was compared to usual care. Primary outcomes were adherence to 18 PD care quality indicators. Secondary outcomes were patient-centered outcome measures. Data sources were telephone survey and electronic medical record (EMR). Outcomes were analyzed as intent-to-treat comparing initial and final survey and repeated-measures mixed-effects models.

resultsAverage age was 71 years; 97% of participants were male. Mean proportion of participants receiving recommended PD care indicators was significantly higher for the intervention than for usual care (0.77 vs 0.58) (mean difference 0.19, 95% confidence interval [CI] 0.16, 0.22). Of 8 secondary outcomes, the only significant difference of the changes over time was in the positive Patient Health Questionnaire-2 depression screen for intervention minus usual care (-11.52 [95% CI -20.42, -2.62]).

conclusionA nurse-led chronic care management intervention, Care Coordination for Health Promotion and Activities in Parkinson's Disease (CHAPS), substantially increased adherence to PD quality of care indicators among veterans with PD, as documented in the EMR. Of 8 secondary outcomes assessed, a screening measure for depressive symptomatology was the only measure that was better in the intervention compared to usual care. More telephone calls in CHAPS were the only utilization difference over usual care. While CHAPS appears promising for improving PD care, additional iterative research is needed to refine the CHAPS model in routine clinical care so that it measurably improves patient-centered outcomes (NCT01532986). CLASSIFICATION OF EVIDENCE: This study provides Class I evidence that for patients with PD, CHAPS increased adherence to PD quality of care indicators.

Indexed as

Quality ImprovementAgedDisease ManagementFemaleFollow-Up StudiesHealth PromotionHumansMaleNursesParkinson DiseaseTreatment Adherence and ComplianceTreatment OutcomeVeterans

Identifiers

PMID30902908
PMCPMC6550506
OpenAlexW2935997096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.