Evidence map›Paper›PMID 30902903›Full record

ArticleJournal of lipid research2019

Acylation derivatization based LC-MS analysis of 25-hydroxyvitamin D from finger-prick blood.

Juan Le娟乐, Teng-Fei Yuan飞袁腾, Jia-Qing Geng庆耿嘉, Shao-Ting Wang亭王少, Yan Li艳李, Bing-Hong Zhang宏张炳

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Juan Le娟乐Department of Clinical Laboratory Renmin Hospital of Wuhan University, 430060 Wuhan, China.
Teng-Fei Yuan飞袁腾Department of Clinical Laboratory Renmin Hospital of Wuhan University, 430060 Wuhan, China.
Jia-Qing Geng庆耿嘉Pediatric Department Renmin Hospital of Wuhan University, 430060 Wuhan, China.
Shao-Ting Wang亭王少Department of Clinical Laboratory Renmin Hospital of Wuhan University, 430060 Wuhan, China. Electronic address: shaotingw@163.com.
Yan Li艳李Department of Clinical Laboratory Renmin Hospital of Wuhan University, 430060 Wuhan, China.
Bing-Hong Zhang宏张炳Pediatric Department Renmin Hospital of Wuhan University, 430060 Wuhan, China.
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D metabolite analysis possessed significant clinical value for the pediatric department. However, invasive venipuncture sampling and high blood consumption inflicted much suffering on patients. For alleviation, we carried out a LC-MS method for 25-hydroxyvitamin D quantification in only 3 μl of plasma from the considerably less invasive finger-prick blood samples. To improve sensitivity, acylation on C3-hydroxyl (by isonicotinoyl chloride) rather than Diels-Alder adduction on s-

Indexed as

Blood Specimen CollectionFingersAcylationChromatography, LiquidCohort StudiesHumansInfantInfant, NewbornTandem Mass SpectrometryVitamin D25-hydroxyvitamin DVitamin Dliquid chromatography-mass spectrometryneonatal jaundicevitamin D

Identifiers

PMID30902903
PMCPMC6495167
OpenAlexW2923415542

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.