Evidence map›Paper›PMID 30902808›Full record

ArticleGenetics2019

Genome-Wide Discovery of DEAD-Box RNA Helicase Targets Reveals RNA Structural Remodeling in Transcription Termination.

Yu-Hsuan Lai, Krishna Choudhary, Sara C Cloutier, Zheng Xing, Sharon Aviran, Elizabeth J Tran

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

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  11. Gle1 is required for tRNA to stimulate Dbp5 ATPase activitybioRxiv : the preprint server for biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yu-Hsuan LaiDepartment of Biochemistry, Purdue University, West Lafayette, Indiana 47907-2063.ORCID 0000-0002-3632-5670
Krishna ChoudharyDepartment of Biomedical Engineering and Genome Center, University of California, Davis, California 95616.ORCID 0000-0002-7966-1527
Sara C CloutierDepartment of Biochemistry, Purdue University, West Lafayette, Indiana 47907-2063.ORCID 0000-0002-3088-8843
Zheng XingDepartment of Biochemistry, Purdue University, West Lafayette, Indiana 47907-2063.ORCID 0000-0002-8610-0031
Sharon AviranDepartment of Biomedical Engineering and Genome Center, University of California, Davis, California 95616 ejtran@purdue.edu saviran@ucdavis.edu.ORCID 0000-0003-1872-9820
Elizabeth J TranDepartment of Biochemistry, Purdue University, West Lafayette, Indiana 47907-2063 ejtran@purdue.edu saviran@ucdavis.edu.ORCID 0000-0002-9541-004X
Purdue University West Lafayette · USUniversity of California, Davis · USCenter for Cancer Research · US

Funding

Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI Andrea L Kasinski · 1985 to 2026
$43.4M
The Role of DEAD-box Proteins in Gene ExpressionR01GM097332 · NIGMS · PURDUE UNIVERSITY · PI TRAN, ELIZABETH J · 2011 to 2025
$4.1M
Methods for RNA structural analysis using computation and structure mapping experR00HG006860 · NHGRI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI AVIRAN, SHARON · 2014 to 2016
$725k
NCI NIH HHS P30 CA023168NHGRI NIH HHS R00 HG006860NIGMS NIH HHS R01 GM097332
6 · The paper itself

Abstract

RNA helicases are a class of enzymes that unwind RNA duplexes

Indexed as

Transcription Termination, GeneticDEAD-box RNA HelicasesDNA HelicasesGene Expression Regulation, FungalNuclear ProteinsRNA-Binding ProteinsRNA HelicasesRNA, MessengerRNA Polymerase IIRNA, Small NucleolarSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence Analysis, RNADbp2 protein, S cerevisiaeDEAD-box RNA HelicasesDNA HelicasesNAB3 protein, S cerevisiaeNRD1 protein, S cerevisiaeNuclear ProteinsRNA-Binding ProteinsRNA HelicasesRNA, MessengerRNA Polymerase IIRNA, Small NucleolarSaccharomyces cerevisiae ProteinsSEN1 protein, S cerevisiaeDEAD-boxRNA helicaseRNA structureterminationtranscription

Identifiers

PMID30902808
PMCPMC6499532
OpenAlexW2943287776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.