Evidence map›Paper›PMID 30902564›Full record

ArticleAmerican journal of preventive medicine2019

One Hour a Week: Moving to Prevent Disability in Adults With Lower Extremity Joint Symptoms.

Dorothy D Dunlop, Jing Song, Jennifer M Hootman, Michael C Nevitt, Pamela A Semanik, Jungwha Lee, Leena Sharma, Charles B Eaton, Marc C Hochberg, Rebecca D Jackson and 2 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in American journal of preventive medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Dorothy D DunlopDepartment of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois; Department of Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois. Electronic address: ddunlop@northwestern.edu.
Jing SongInstitute of Public Health and Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois.
Jennifer M HootmanArthritis Program, Division of Population Health, Centers for Disease Control and Prevention, Atlanta, Georgia.
Michael C NevittDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
Pamela A SemanikDepartment of Adult Health and Gerontological Nursing, Rush University, College of Nursing, Chicago, Illinois.
Jungwha LeeDepartment of Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois.
Leena SharmaDepartment of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois.
Charles B EatonDepartment of Family Medicine, Brown University, Alpert Medical School, Pawtucket, Rhode Island; Department of Epidemiology, Brown University, Alpert Medical School, Pawtucket, Rhode Island.
Marc C HochbergDepartment of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland; Department of Epidemiology and Public Health, University of Maryland, School of Medicine, Baltimore, Maryland.
Rebecca D JacksonDepartment of Internal Medicine, The Ohio State University, Columbus, Ohio.
C Kent KwohDepartment of Medicine, University of Arizona, College of Medicine, Tucson, Arizona; Department of Medical Imaging, University of Arizona, College of Medicine, Tucson, Arizona.
Rowland W ChangDepartment of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois; Department of Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois; Department of Physical Medicine and Rehabilitation, Northwestern University, Feinberg School of Medicine, Chicago, Illinois.
Northwestern University · USBrown University · USCenters for Disease Control and Prevention · USRush University · USThe Ohio State University · USUniversity of Arizona · USUniversity of California, San Francisco · USUniversity of Maryland, Baltimore · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Study of Lupus Vascular and Bone Longterm EndpointsP60AR048098 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RAMSEY-GOLDMAN, ROSALIND · 2002 to 2011
$11.4M
Resource CoreP30AR072579 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Jungwha Julia Lee · 2017 to 2026
$8.3M
Long-term Significance of Pre-radiographic Lesions in Persons at Risk for Knee OAR01AR065473 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SHARMA, LEENA · 2014 to 2018
$5.7M
Physical Activity Changes & Thersholds: Quality of Life and Outcomes in Knee OAP60AR064464 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SHARMA, LEENA · 2013 to 2017
$4.5M
The Effect of Physical Activity on Disability Progression in Knee OAR01AR054155 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DUNLOP, DOROTHY D. · 2008 to 2016
$3.6M
NEW PHARMACOLOGY ASPECTS RELATED TO CARBONIC ANHYDRASER01HL022258 · NHLBI · UNIVERSITY OF FLORIDA · PI MAREN, THOMAS H · 1985 to 1986
–
CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVE-N01AR22260N01AR022260 · NIAMS · UNIVERSITY OF PITTSBURGH · PI KWOH, KENT · 2002 to 2006
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CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVE-264022259-264022259N01AR022259 · NIAMS · UNIVERSITY OF MARYLAND AT BALT · PI HOCHBERG, MARC C. · 2002 to 2006
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CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVE-N01AR22261N01AR022261 · NIAMS · OHIO STATE UNIVERSITY RESEARCH · PI JACKSON, REBECCA · 2002 to 2006
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CLINICAL CENTER FOR THE OSTEOARTHRITIS-264022262-264022262N01AR022262 · NIAMS · THE MEMORIAL HOSPITAL · PI ASSAF, ANNLOUISE R. · 2002 to 2006
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DATA COORDINATING CENTER FOR THE OSTEOARTHRITIS INITIATIVE-264022258N01AR022258 · NIAMS · UNIVERSITY OF CALIFORNIA SYS OFFICE/PRES · 2003 to 2003
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NCATS NIH HHS UL1 TR001422NHLBI NIH HHS N01 AR022258NIAMS NIH HHS N01 AR022259NIAMS NIH HHS N01 AR022260NIAMS NIH HHS N01 AR022261NIAMS NIH HHS N01 AR022262NIAMS NIH HHS P30 AR072579NIAMS NIH HHS P60 AR048098NIAMS NIH HHS P60 AR064464NIAMS NIH HHS R01 AR054155NIAMS NIH HHS R01 AR065473
6 · The paper itself

Abstract

introductionPhysical activity guidelines recommend minimum thresholds. This study sought to identify evidence-based thresholds to maintain disability-free status over 4years among adults with lower extremity joint symptoms.

methodsProspective multisite Osteoarthritis Initiative accelerometer monitoring cohort data from September 2008 through December 2014 were analyzed. Adults (n=1,564) aged ≥49years at elevated disability risk because of lower extremity joint symptoms were analyzed for biennial assessments of disability-free status from gait speed ≥1meter/second (mobility disability-free) and self-report of no limitations in activities of daily living (activities of daily living disability-free). Classification tree analyses conducted in 2017-2018 identified optimal thresholds across candidate activity intensities (sedentary, light, moderate-vigorous, total light and moderate-vigorous activity, and moderate-vigorous accrued in bouts lasting ≥10 minutes).

resultsMinimal thresholds of 56 and 55 moderate-vigorous minutes/week best predicted disability-free status over 4years from mobility and activities of daily living disabilities, respectively, across the candidate measures. Thresholds were consistent across sex, BMI, age, and knee osteoarthritis presence. Mobility disability onset was one eighth as frequent (3% vs 24%, RR=0.14, 95% CI=0.09, 0.20) and activities of daily living disability onset was almost half (12% vs 23%, RR=0.55, 95% CI=0.44, 0.70) among people above versus below the minimum threshold.

conclusionsAttaining an evidence-based threshold of approximately 1-hour moderate-vigorous activity/week significantly increased the likelihood of maintaining disability-free status over 4years. This minimum threshold tied to maintaining independent living abilities has value as an intermediate goal to motivate adults to take action towards the many health benefits of a physically active lifestyle.

Indexed as

ExerciseExercise ToleranceActigraphyAgedDisability EvaluationFemaleHealth StatusHumansKnee JointMaleMiddle AgedOsteoarthritis, KneePredictive Value of TestsProspective StudiesRecovery of FunctionRisk Factors

Identifiers

PMID30902564
PMCPMC6475497
OpenAlexW2923892656

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.