Evidence map›Paper›PMID 30902074›Full record

ArticleBMC cancer2019

Molecular iodine exerts antineoplastic effects by diminishing proliferation and invasive potential and activating the immune response in mammary cancer xenografts.

Irasema Mendieta, Rosa E Nuñez-Anita, Mario Nava-Villalba, Xóchitl Zambrano-Estrada, Evangelina Delgado-González, Brenda Anguiano, Carmen Aceves

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Irasema MendietaInstituto de Neurobiología, UNAM-Juriquilla, 76230, Querétaro, Mexico.
Rosa E Nuñez-AnitaFacultad de Medicina Veterinaria y Zootecnia UMSNH, Michoacán, Mexico.
Mario Nava-VillalbaInstituto de Neurobiología, UNAM-Juriquilla, 76230, Querétaro, Mexico.
Xóchitl Zambrano-EstradaInstituto de Neurobiología, UNAM-Juriquilla, 76230, Querétaro, Mexico.
Evangelina Delgado-GonzálezInstituto de Neurobiología, UNAM-Juriquilla, 76230, Querétaro, Mexico.
Brenda AnguianoInstituto de Neurobiología, UNAM-Juriquilla, 76230, Querétaro, Mexico.
Carmen AcevesInstituto de Neurobiología, UNAM-Juriquilla, 76230, Querétaro, Mexico. caracev@unam.mx.ORCID http://orcid.org/0000-0001-9418-8304
Universidad Michoacana de San Nicolás de Hidalgo · MXUniversidad Nacional Autónoma de México · MX

Funding

CONACYT 176911CONACYT 235961PAPIIT-UNAM 201516PAPIIT-UNAM 209717
6 · The paper itself

Abstract

backgroundThe immune system is a crucial component in cancer progression or regression. Molecular iodine (I

methodsThe present work analyzed the effect of I

resultsIn vitro analysis showed that the 200 μM I

conclusionsI

Indexed as

AnimalsAntineoplastic AgentsBreast NeoplasmsCD8-Positive T-LymphocytesCell MovementCell ProliferationFemaleForkhead Transcription FactorsHumansImmunity, CellularIodineLymphocytes, Tumor-InfiltratingMiceMice, NudeMice, TransgenicNeoplasm InvasivenessAntineoplastic AgentsForkhead Transcription FactorsIodineWhn proteinImmune responseIodineMammary cancerMCF-12FMCF-7MDA-MB231Molecular iodinePPARγXenografts

Identifiers

PMID30902074
PMCPMC6431076
OpenAlexW2922873635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.