Evidence map›Paper›PMID 30901943›Full record

ReviewCancers2019

Perioperative Treatment in Resectable Gastric Cancer: Current Perspectives and Future Directions.

Angelica Petrillo, Luca Pompella, Giuseppe Tirino, Annalisa Pappalardo, Maria Maddalena Laterza, Marianna Caterino, Michele Orditura, Fortunato Ciardiello, Eva Lieto, Gennaro Galizia and 2 more

Abstract readReview
In one paragraph

Review in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Current status of neoadjuvant immunotherapy for the treatment of gastric cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Efficacy and safety of FLOT regimenResearch in pharmaceutical sciences · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Angelica PetrilloDivision of Medical Oncology, Department of Precision Medicine, School of Medicine, University of study of Campania "Luigi Vanvitelli", Via Pansini n.5, 80131 Naples, Italy. angelic.petrillo@gmail.com.
Luca PompellaDivision of Medical Oncology, Department of Precision Medicine, School of Medicine, University of study of Campania "Luigi Vanvitelli", Via Pansini n.5, 80131 Naples, Italy. luc32@hotmail.it.
Giuseppe TirinoDivision of Medical Oncology, Department of Precision Medicine, School of Medicine, University of study of Campania "Luigi Vanvitelli", Via Pansini n.5, 80131 Naples, Italy. giuseppett@icloud.com.
Annalisa PappalardoDivision of Medical Oncology, Department of Precision Medicine, School of Medicine, University of study of Campania "Luigi Vanvitelli", Via Pansini n.5, 80131 Naples, Italy. annalisa.pappalardo88@gmail.com.
Maria Maddalena LaterzaDivision of Medical Oncology, Department of Precision Medicine, School of Medicine, University of study of Campania "Luigi Vanvitelli", Via Pansini n.5, 80131 Naples, Italy. marilena_laterza@yahoo.it.
Marianna CaterinoDivision of Medical Oncology, Department of Precision Medicine, School of Medicine, University of study of Campania "Luigi Vanvitelli", Via Pansini n.5, 80131 Naples, Italy. caterinomarianna@gmail.com.
Michele OrdituraDivision of Medical Oncology, Department of Precision Medicine, School of Medicine, University of study of Campania "Luigi Vanvitelli", Via Pansini n.5, 80131 Naples, Italy. michele.orditura@unicampania.it.
Fortunato CiardielloDivision of Medical Oncology, Department of Precision Medicine, School of Medicine, University of study of Campania "Luigi Vanvitelli", Via Pansini n.5, 80131 Naples, Italy. fortunato.ciardiello@unicampania.it.
Eva LietoDivision of GI Tract Surgical Oncology, Department of Surgical Sciences, University of study of Campania "Luigi Vanvitelli", Via Pansini n.5, 80131 Naples, Italy. eva.lieto@unicampania.it.
Gennaro GaliziaDivision of GI Tract Surgical Oncology, Department of Surgical Sciences, University of study of Campania "Luigi Vanvitelli", Via Pansini n.5, 80131 Naples, Italy. gennaro.galizia@unicampania.it.
Carlo CastoroDepartment of upper GI surgery, Humanitas Research Hospital-Humanitas University, 20089 Rozzano (Milano), Italy. carlo.castoro@hunimed.eu.
Ferdinando De VitaDivision of Medical Oncology, Department of Precision Medicine, School of Medicine, University of study of Campania "Luigi Vanvitelli", Via Pansini n.5, 80131 Naples, Italy. ferdinando.devita@unicampania.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) is the fifth-most common cancer worldwide and an important cause of cancer-related-death. The growing knowledge of its molecular pathogenesis has shown that GC is not a single entity, but a constellation of different diseases, each with its own molecular and clinical characteristics. Currently, surgery represents the only curative approach for localized GC, but only 20% of patients (pts) showed resectable disease at diagnosis and, even in case of curative resection, the prognosis remains poor due to the high rate of disease relapse. In this context, multimodal perioperative approaches were developed in western and eastern countries in order to decrease relapse rates and improve survival. However, there is little consensus about the optimal treatment for non-metastatic GC. In this review, we summarize the current status and future developments of perioperative chemotherapy in resectable GC, attempting to find clear answers to the real problems in clinical practice.

Indexed as

gastric cancerneoadjuvant chemotherapyperioperative treatment

Identifiers

PMID30901943
PMCPMC6468561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.