Evidence map›Paper›PMID 30901914›Full record

ArticleJournal of clinical medicine2019

Long-Term Effects of Initiating Continuous Subcutaneous Insulin Infusion (CSII) and Continuous Glucose Monitoring (CGM) in People with Type 1 Diabetes and Unsatisfactory Diabetes Control.

Jon-Duri Senn, Stefan Fischli, Lea Slahor, Susanne Schelbert, Christoph Henzen

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  7. The Do-It-Yourself Artificial Pancreas: A Comprehensive Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jon-Duri SennDivision of Endocrinology, Diabetology, and Clinical Nutrition, Department of Medicine, Lucerne Cantonal Hospital, CH-6000 Lucerne 16, Switzerland. jonduri.senn@unibas.ch.ORCID 0000-0001-9554-8025
Stefan FischliDivision of Endocrinology, Diabetology, and Clinical Nutrition, Department of Medicine, Lucerne Cantonal Hospital, CH-6000 Lucerne 16, Switzerland. stefan.fischli@luks.ch.
Lea SlahorDivision of Endocrinology, Diabetology, and Clinical Nutrition, Department of Medicine, Lucerne Cantonal Hospital, CH-6000 Lucerne 16, Switzerland. lea.slahor@luks.ch.
Susanne SchelbertDivision of Endocrinology, Diabetology, and Clinical Nutrition, Department of Medicine, Lucerne Cantonal Hospital, CH-6000 Lucerne 16, Switzerland. susanne.schelbert@luks.ch.
Christoph HenzenDivision of Endocrinology, Diabetology, and Clinical Nutrition, Department of Medicine, Lucerne Cantonal Hospital, CH-6000 Lucerne 16, Switzerland. christoph.henzen@luks.ch.ORCID 0000-0002-7075-8947

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to assess the long-term effects of the introduction of continuous subcutaneous insulin infusion (CSII) and continuous glucose monitoring (CGM) in people with type 1 diabetes (T1D).

methodsA prospective single-centre cohort study including participants with T1D and HbA1c > 7.5%. After completing a course in flexible intensified insulin treatment (FIT), participants were offered treatment change to CSII/CGM. FIT participants with HbA1c ≤ 7.5% who remained on multiple daily injections (MDI) and without CGM were monitored as a separate cohort to compare the cumulative incidence of diabetic complications.

resultsThe study cohort included 41 participants with T1D (21 male/20 female). The mean age (±SD) at inclusion was 24.2 ± 10.9 years, the mean follow-up was 8.9 ± 2.8 years, and the mean diabetes duration at the end of the study was 15.9 ± 10.1 years. The mean HbA1c level before the introduction of CSII was 8.8 ± 1.3% (73 ± 8 mmol/mol), and decreased significantly thereafter to 8.0 ± 1.1% (63 ± 7 mmol/mol) (

conclusionIn people with T1D and unsatisfactory diabetes control the introduction of CSII and CGM results in a substantial and long-term improvement.

Indexed as

continuous glucose monitoringcontinuous subcutaneous insulin infusionfunctional insulin therapyinsulin pumpType 1 diabetes

Identifiers

PMID30901914
PMCPMC6463068

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.