Evidence map›Paper›PMID 30901813›Full record

ArticleMaterials (Basel, Switzerland)2019

Luminescent Mesoporous Silica Nanohybrid Based on Drug Derivative Terbium Complex.

Fernando E Maturi, Rafael M Sábio, Robson R Silva, Marcelo G Lahoud, Andréia B Meneguin, Gustavo T Valente, Raphael A Caface, Ilaiáli S Leite, Natalia M Inada, Sidney J L Ribeiro

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Red-Emitting Hybrid Based on EuMaterials (Basel, Switzerland) · 2020
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Fernando E MaturiInstitute of Chemistry, São Paulo State University-UNESP, 14800-060 Araraquara-SP, Brazil. fernando.maturi@unesp.br.ORCID 0000-0002-9305-8185
Rafael M SábioSão Carlos Institute of Physics, University of São Paulo-USP, 13560-970 São Carlos-SP, Brazil. rafaelmsabio@gmail.com.ORCID 0000-0002-3852-2184
Robson R SilvaSão Carlos Institute of Physics, University of São Paulo-USP, 13560-970 São Carlos-SP, Brazil. robsilva31@usp.br.
Marcelo G LahoudInstitute of Chemistry, São Paulo State University-UNESP, 14800-060 Araraquara-SP, Brazil. marcelo_lahoud@hotmail.com.
Andréia B MeneguinSão Carlos Institute of Physics, University of São Paulo-USP, 13560-970 São Carlos-SP, Brazil. abagliottim@hotmail.com.
Gustavo T ValenteSão Carlos Institute of Physics, University of São Paulo-USP, 13560-970 São Carlos-SP, Brazil. gtvfisica@gmail.com.
Raphael A CafaceSão Carlos Institute of Physics, University of São Paulo-USP, 13560-970 São Carlos-SP, Brazil. raphaelcaface@gmail.com.
Ilaiáli S LeiteSão Carlos Institute of Physics, University of São Paulo-USP, 13560-970 São Carlos-SP, Brazil. ilaiali.leite@usp.br.
Natalia M InadaSão Carlos Institute of Physics, University of São Paulo-USP, 13560-970 São Carlos-SP, Brazil. nataliainada@gmail.com.ORCID 0000-0003-1940-186X
Sidney J L RibeiroInstitute of Chemistry, São Paulo State University-UNESP, 14800-060 Araraquara-SP, Brazil. sidney.jl.ribeiro@unesp.br.
Universidade Federal de São Carlos · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesoporous silica nanoparticles prepared by organic template-driven synthesis have been successfully explored as carriers of the drug-derivate green luminescent complex of terbium (III) with the nonsteroidal anti-inflammatory drug ketoprofen. The terbium (III) complex was synthesized by reacting ketoprofen sodium salt with terbium (III) chloride, which was further adsorbed onto the surface of mesoporous nanoparticles with a mean particle size of 47 ± 4 nm and pore size of 11 nm. The incorporation of the complex into mesoporous silica nanoparticles was tracked by the decrease in the surface area and pore size of the nanoparticles, and successfully demonstrated by substantial changes in the adsorption isotherms and thermal and vibrational spectroscopy results. The cytotoxicity assay and confocal microscopy have shown that the novel luminescent nanohybrid presents high cell viability and the characteristic terbium (III) emission can be assessed through two-photon excitation, which paves the way for bioimaging applications in nanomedicine.

Indexed as

ketoprofenluminescent nanohybridmesoporous silica nanoparticlesterbiumtwo-photon

Identifiers

PMID30901813
PMCPMC6471776
OpenAlexW2924790514

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.