Evidence map›Paper›PMID 30901277›Full record

ReviewAmerican journal of physiology. Heart and circulatory physiology2019

Role of T-cell activation in salt-sensitive hypertension.

Jiafa Ren, Steven D Crowley

Open access · bronzeAbstract readReview
In one paragraph

Review in American journal of physiology. Heart and circulatory physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 48 citations in OpenAlex.

  1. Female Dahl, but Not SS13Research square · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Immunology of Hypertension: Pathophysiological and Therapeutic Aspects.International journal of molecular sciences · 2025
    Review
  8. Article
  9. Review
  10. Review
  11. Recent advances on immunity and hypertension: the new cells on the kidney block.American journal of physiology. Renal physiology · 2025
    Review
  12. Article
  13. Hypertension (Dallas, Tex. : 1979) · 2024
    Article
  14. Immune cells and hypertension.Immunologic research · 2024
    Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jiafa RenDivision of Nephrology, Department of Medicine, Durham Veterans Affairs and Duke University Medical Centers , Durham, North Carolina.
Steven D CrowleyDivision of Nephrology, Department of Medicine, Durham Veterans Affairs and Duke University Medical Centers , Durham, North Carolina.
Durham VA Medical Center · US

Funding

Role of Th1 Immune Responses in the Pathogenesis of Hypertensive Kidney InjuryR01DK087893 · NIDDK · DUKE UNIVERSITY · PI CROWLEY, STEVEN D · 2010 to 2018
$2.4M
Role of Dendritic Cell-mediated T Cell Activation in Salt-sensitive HypertensionR01HL128355 · NHLBI · DUKE UNIVERSITY · PI CROWLEY, STEVEN D · 2016 to 2019
$1.9M
BLRD VA I01 BX000893NHLBI NIH HHS R01 HL128355NIDDK NIH HHS R01 DK087893
6 · The paper itself

Abstract

The contributions of T lymphocytes to the pathogenesis of salt-sensitive hypertension has been well established. Under hypertensive stimuli, naive T cells develop into different subsets, including Th1, Th2, Th17, Treg, and cytotoxic CD8

Indexed as

Blood PressureLymphocyte ActivationAnimalsCellular MicroenvironmentDisease ProgressionHeart DiseasesHumansHypertensionKidney DiseasesPhenotypeSignal TransductionSodium Chloride, DietaryT-Lymphocyte SubsetsSodium Chloride, Dietaryend-organ damagehypertensionsaltT cell

Identifiers

PMID30901277
PMCPMC6620682
OpenAlexW2937020661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.