ArticleBrain connectivity2019
Children with Autism Spectrum Disorder Demonstrate Regionally Specific Altered Resting-State Phase-Amplitude Coupling.
Article in Brain connectivity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Differential GABA dynamics across brain functional networks in autism.Communications biology · 2026Trial
- Oxytocin impacts top-down and bottom-up social perception in adolescents with ASD: a MEG study of neural connectivity.Molecular autism · 2022Trial
- MEG resting state alpha and beta band functional connectivity in male children with autism and sensory processing dysfunction.Journal of neural engineering · 2026Article
- Widespread Hyper-Coupling and Frequency-Specific Dysregulation of Phase-Amplitude Coupling in Young Children with Autism Spectrum Disorder.Brain sciences · 2026Article
- Differential late-stage face processing in autism: a magnetoencephalographic study of fusiform gyrus activation.BMC psychiatry · 2024Article
- Model selection to achieve reproducible associations between resting state EEG features and autism.Scientific reports · 2024Article
- Correlation between autistic traits and brain functional connectivity in preschoolers with autism spectrum disorder: a resting state MEG study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Resting-State Activity in Children: Replicating and Extending Findings of Early Maturation of Alpha Rhythms in Autism Spectrum Disorder.Journal of autism and developmental disorders · 2024Article
- Voltage-gated potassium channels as a potential therapeutic target for the treatment of neurological and psychiatric disorders.Frontiers in cellular neuroscience · 2024Review
- Heterogeneity and convergence across seven neuroimaging modalities: a review of the autism spectrum disorder literature.Frontiers in psychiatry · 2024Review
- A Fusion-Based Machine Learning Approach for Autism Detection in Young Children Using Magnetoencephalography Signals.Journal of autism and developmental disorders · 2023Article
- Peak Alpha Frequency and Thalamic Structure in Children with Typical Development and Autism Spectrum Disorder.Journal of autism and developmental disorders · 2022Article
- Children with autism spectrum disorder show altered functional connectivity and abnormal maturation trajectories in response to inverted faces.Autism research : official journal of the International Society for Autism Research · 2021Article
- Shifted phase of EEG cross-frequency coupling in individuals with Phelan-McDermid syndrome.Molecular autism · 2021Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Studies suggest that individuals with autism spectrum disorder (ASD) exhibit altered electrophysiological alpha to gamma phase-amplitude coupling (PAC). Preliminary reports with small samples report conflicting findings regarding the directionality of the alpha to gamma PAC alterations in ASD. The present study examined resting-state activity throughout the brain in a relatively large sample of 119 children with ASD and 47 typically developing children. Children with ASD demonstrated regionally specific abnormalities in alpha to low-gamma PAC, with increased alpha to low-gamma PAC for a central midline source and decreased PAC at lateral sources. Group differences in local gamma-band power did not account for the regional group differences in alpha to low-gamma PAC. Moreover, local alpha power did not significantly modulate alpha to low-gamma PAC estimates. Finally, PAC estimates were correlated with Social Responsiveness Scale (SRS) indicating clinical relevance of the PAC metric. In conclusion, alpha to low-gamma PAC alterations in ASD demonstrate a heterogeneous spatial profile consistent with previous studies and were related to symptom severity.
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