Evidence map›Paper›PMID 30900408›Full record

Trial reportObesity (Silver Spring, Md.)2019

Randomized Controlled Trial of Home-Based Lifestyle Therapy on Postpartum Weight in Underserved Women with Overweight or Obesity.

Debra Haire-Joshu, Alison G Cahill, Richard I Stein, W Todd Cade, Candice L Woolfolk, Kelle Moley, Amit Mathur, Cynthia D Schwarz, Kenneth B Schechtman, Samuel Klein

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06773299 (ENhancing Intergenerational HeAlth in Nigeria), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06773299 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

ENhancing Intergenerational HeAlth in Nigeria: Peripartum as Critical Life StagE for CardioVascular Health

TypeinterventionalSponsorWashington University School of MedicineRan2025 to 2028Enrolled1,000ConditionsHypertension in Pregnancy, Hypertension, Obesity and Overweight, Maternal Morbidity and MortalityArmsPAT+HEALTH curriculum - Nigeria
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  10. Review
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  12. Disparities in Access and Quality of Obesity Care.Gastroenterology clinics of North America · 2023
    Review
  13. Review
  14. Review
  15. Article
  16. New research directions on disparities in obesity and type 2 diabetes.Annals of the New York Academy of Sciences · 2020
    Article
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Debra Haire-JoshuBrown School, Washington University in St. Louis, St. Louis, Missouri, USA.
Alison G CahillDepartment of Obstetrics and Gynecology, Washington University in St. Louis, St. Louis, Missouri, USA.ORCID 0000-0002-6012-3374
Richard I SteinCenter for Human Nutrition, Washington University in St. Louis, St. Louis, Missouri, USA.
W Todd CadeProgram in Physical Therapy, Washington University in St. Louis, St. Louis, Missouri, USA.
Candice L WoolfolkDepartment of Obstetrics and Gynecology, Washington University in St. Louis, St. Louis, Missouri, USA.
Kelle MoleyDepartment of Obstetrics and Gynecology, Washington University in St. Louis, St. Louis, Missouri, USA.
Amit MathurDepartment of Pediatrics, Washington University in St. Louis, St. Louis, Missouri, USA.
Cynthia D SchwarzBrown School, Washington University in St. Louis, St. Louis, Missouri, USA.ORCID 0000-0002-4396-2897
Kenneth B SchechtmanDepartment of Biostatistics, Washington University in St. Louis, St. Louis, Missouri, USA.
Samuel KleinCenter for Human Nutrition, Washington University in St. Louis, St. Louis, Missouri, USA.

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational Sciences (UL1)UL1RR024992 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$45.4M
Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
TRANSGENICS COREP60DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI SCHAFFER, JEAN E. · 1986 to 2012
$25.2M
Washington University Center for Diabetes Translation Research P30DK092950 · NIDDK · WASHINGTON UNIVERSITY · PI Ross C Brownson, Debra Haire-Joshu · 2011 to 2026
$11.7M
Weight Management in Obese Pregnant Underserved African American WomenU01DK094416 · NIDDK · WASHINGTON UNIVERSITY · PI CAHILL, ALISON G, HAIRE-JOSHU, DEBRA · 2011 to 2017
$5.3M
Lifestyle Interventions in Overweight and Obese Pregnant WomenU01DK094463 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI GALLAGHER, DYMPNA, PI-SUNYER, XAVIER · 2011 to 2017
$5.3M
Maternal-Offspring Metabolics: Family Intervention Trial (MOMFIT)U01HL114344 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PEACEMAN, ALAN M, VAN HORN, LINDA VERNER · 2011 to 2017
$4.9M
Preventing excessive gestational weight gain in obese womenU01HL114377 · NHLBI · CALIFORNIA POLY STATE U SAN LUIS OBISPO · PI PHELAN, SUZANNE · 2011 to 2016
$4.5M
RCU for Lifestyle Interventions in Overweight and Obese Pregnant Women ConsortiumU01DK094466 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI CLIFTON, REBECCA GERSNOVIEZ, DREWS, KIMBERLY LEE · 2011 to 2016
$4.1M
Pregnancy and EARly Lifestyle improvement Study (PEARLS)U01HD072834 · NICHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI FRANKS, PAUL WILLIAM, JOSHIPURA, KAUMUDI J · 2011 to 2016
$3.7M
NCATS NIH HHS UL1 TR002345NCRR NIH HHS UL1 RR024992NHLBI NIH HHS U01 HL114344NHLBI NIH HHS U01 HL114377NICHD NIH HHS U01 HD072834NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK056341NIDDK NIH HHS P30 DK092950NIDDK NIH HHS P60 DK020579NIDDK NIH HHS U01 DK094416NIDDK NIH HHS U01 DK094418NIDDK NIH HHS U01 DK094463NIDDK NIH HHS U01 DK094466
6 · The paper itself

Abstract

objectiveThis study aimed to assess the efficacy of a home-based lifestyle intervention delivered through Parents as Teachers (PAT), a national home-visiting organization, designed to minimize excessive weight gain through 12 months post partum in socioeconomically disadvantaged (SED) African American women with overweight or obesity.

methodsThis randomized controlled trial was conducted at a single center as part of the Lifestyle Interventions for Expectant Moms (LIFE-Moms) consortium. Analysis was conducted with 185 SED African American women (BMI 25.0-45.0 kg/m

resultsCompared with standard PAT, the PAT+Lifestyle group gained less weight (2.5 kg vs. 5.7 kg; P = 0.01) and were more likely to return to their baseline weight (38.0% vs. 21.5%; P = 0.01) from baseline to 12 months post partum. There were no differences between groups in cardiometabolic outcomes, indices of glycemic control and insulin sensitivity, and plasma lipid profile. The estimated cost of PAT+Lifestyle was $81 more to deliver per family than standard PAT.

conclusionsPAT+Lifestyle decreases weight gain during pregnancy through 12 months post partum in SED African American women with overweight or obesity at the start of pregnancy with minimal additional cost.

Indexed as

Vulnerable PopulationsWeight GainAdolescentAdultBehavior TherapyBlack or African AmericanBlood GlucoseBody WeightFemaleHome Care ServicesHumansLife StyleMiddle AgedObesityOverweightPostnatal CareBlood Glucose

Identifiers

PMID30900408
PMCPMC6526535

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.