Evidence map›Paper›PMID 30900206›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019

Food-related quality of life in patients with inflammatory bowel disease and irritable bowel syndrome.

Livia Guadagnoli, Ece A Mutlu, Bethany Doerfler, Ammoura Ibrahim, Darren Brenner, Tiffany H Taft

Abstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Irritable bowel syndrome.Nature reviews. Disease primers · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. [Dietary Therapy in Irritable Bowel Syndrome].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Livia GuadagnoliDivision of Gastroenterology & Hepatology, Northwestern University Feinberg School of Medicine, 676 N. Saint Clair Street Suite 1400, Chicago, IL, 60611, USA.
Ece A MutluDivision of Digestive Diseases and Nutrition, Rush Medical College, Chicago, IL, USA.
Bethany DoerflerDivision of Gastroenterology & Hepatology, Northwestern University Feinberg School of Medicine, 676 N. Saint Clair Street Suite 1400, Chicago, IL, 60611, USA.
Ammoura IbrahimDivision of Digestive Diseases and Nutrition, Rush Medical College, Chicago, IL, USA.
Darren BrennerDivision of Gastroenterology & Hepatology, Northwestern University Feinberg School of Medicine, 676 N. Saint Clair Street Suite 1400, Chicago, IL, 60611, USA.
Tiffany H TaftDivision of Gastroenterology & Hepatology, Northwestern University Feinberg School of Medicine, 676 N. Saint Clair Street Suite 1400, Chicago, IL, 60611, USA. ttaft@northwestern.edu.ORCID http://orcid.org/0000-0002-4670-2441

Funding

The mechanics of symptom generation in dysphagiaR01DK079902 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PANDOLFINO, JOHN E · 2009 to 2017
$2.9M
Diet modulation of bacterial sulfur & bile acid metabolism and colon cancer riskR01CA204808 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI GASKINS, REX, MUTLU, ECE A. · 2016 to 2020
$2.0M
Training Grant in Gastrointestinal Physiology and PsychologyT32DK101363 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PANDOLFINO, JOHN E · 2014 to 2018
$1.2M
NCI NIH HHS R01 CA204808NIDDK NIH HHS L30 DK089436NIDDK NIH HHS R01CA204808NIDDK NIH HHS R01 DK079902NIDDK NIH HHS R01DK079902NIDDK NIH HHS T32 DK101363NIDDK NIH HHS T32DK101363
6 · The paper itself

Abstract

backgroundFood-related quality of life (FRQoL) evaluates the impact of diet, eating behaviors, and food-related anxiety on a person's quality of life. This is the first study to evaluate FRQoL in inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), two illnesses where food and diet are of importance.

methodsOne hundred seventy-five participants (80 IBS, 95 IBD) participated in the study by completing measures evaluating FRQoL, psychological distress, and health-related quality of life. Primary analyses evaluated differences in FRQoL between IBD and IBS patients. Secondary analyses compared differences based on remission status, dietary use, and dietary consultation, as well as evaluated potential predictors of FRQoL.

resultsIBD patients in remission report the highest FRQoL (IBD-remission: 91.2 (26.5) vs. IBD-active: 67.7 (19.6) and IBS-active: 67.6 (18.3), p < .001). Using more dietary treatments is associated with decreased FRQoL for IBS (r = - 0.23, p < .05) and IBD patients (r = - 0.31, p < .01). IBS patients are more likely to use dietary treatments than IBD (IBS = 81% vs. IBD = 64%, p < .01), with self-directed diets being the most commonly used approach. Symptom severity is the strongest predictor of FRQoL in both groups (IBD: R

conclusionFRQoL is a unique construct for IBD and IBS patients that can be influenced by several clinical and dietary factors, including number of diets and type of diet used, depending on the diagnosis. Thus, FRQoL should be considered when working with both IBD and IBS patients.

Indexed as

AdultAgedAnxietyDietFemaleHumansInflammatory Bowel DiseasesIrritable Bowel SyndromeMaleMiddle AgedQuality of LifeYoung AdultDietInflammatory bowel diseaseIrritable bowel syndromeOutcomes researchQuality of life

Identifiers

PMID30900206
PMCPMC6625837

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.