Evidence map›Paper›PMID 30900081›Full record

ArticlePathology oncology research : POR2020

Patients with Plasma Cell Disorders Have High EBV DNA in Peripheral Blood than the General Population.

Kumar Sangam, Yashwant Kumar, Ranjana Walker Minz, Neelam Varma, Subhash Varma, Shashi Anand

Abstract read
PubMed Publisher
In one paragraph

Article in Pathology oncology research : POR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kumar SangamDepartment of Immunopathology, Post Graduate Institute of Medical Education & Research, Chandigarh, India.
Yashwant KumarDepartment of Immunopathology, Post Graduate Institute of Medical Education & Research, Chandigarh, India. dryashwant@ymail.com.ORCID http://orcid.org/0000-0001-6369-3834
Ranjana Walker MinzDepartment of Immunopathology, Post Graduate Institute of Medical Education & Research, Chandigarh, India.
Neelam VarmaDepartment of Immunopathology, Post Graduate Institute of Medical Education & Research, Chandigarh, India.
Subhash VarmaDepartment of Internal Medicine, Post Graduate Institute of Medical Education & Research, Chandigarh, India.
Shashi AnandDepartment of Immunopathology, Post Graduate Institute of Medical Education & Research, Chandigarh, India.

Funding

PGIMER 71/5-Edu/12/1223
6 · The paper itself

Abstract

Epstein-Barr virus (EBV) is involved in the development of a wide range of B cell lympho-proliferative disorders. Its association with plasma cell disorders (PCD) however is not clear, especially in immunocompetent patients. To explore any relationship, 39 patients of suspected PCD with positive M-band on electrophoresis and 50 healthy controls were enrolled. EBV DNA in peripheral blood was quantified using quantitative Real Time Polymerase Chain Reaction (qPCR). Of 39 patients, 15 (38.5%) had EBV DNA compared to 8/50 (16%) controls (p = 0.0008). The mean viral copy number was found to be significantly high in patients compared to controls (1.8 × 10

Indexed as

AdultAgedAged, 80 and overCase-Control StudiesDNA, ViralEpstein-Barr Virus InfectionsFemaleFollow-Up StudiesHerpesvirus 4, HumanHumansIndiaLeukocytes, MononuclearMaleMiddle AgedNeoplasms, Plasma CellPrognosisDNA, ViralEpstein - Barr virusImmunocompetentPlasma cell disordersQuantitative real time PCR

Identifiers

PMID30900081

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.