Evidence map›Paper›PMID 30900072›Full record

ArticleArchives of virology2019

Characterization and genome annotation of a newly detected bacteriophage infecting multidrug-resistant Acinetobacter baumannii.

Zichen Yang, Xinzhu Liu, Yunlong Shi, Supeng Yin, Wei Shen, Jing Chen, Yu Chen, Yajie Chen, Bo You, Yali Gong and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Archives of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Redefining Antimicrobial Resistance inInternational journal of molecular sciences · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. A decade of genomic and phenotypic adaptation of carbapenem-resistantFrontiers in cellular and infection microbiology · 2025
    Article
  9. Article
  10. Review
  11. Lytic Capsule-SpecificViruses · 2024
    Article
  12. NewInternational journal of molecular sciences · 2024
    Article
  13. Article
  14. Functional domains ofFrontiers in microbiology · 2024
    Article
  15. Article
  16. Potential Usefulness of Bacteriophages for the Treatment of Multidrug-ResistantThe Malaysian journal of medical sciences : MJMS · 2023
    Review
  17. Characterization and Genomic Analysis of a Novel Lytic Phage DCp1 againstInternational journal of molecular sciences · 2023
    Article
  18. Article
  19. Review
  20. Isolation and Characterisation of Bacteriophage Selective for KeyPharmaceuticals (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Zichen YangState Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Chongqing, China.
Xinzhu LiuState Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Chongqing, China.
Yunlong ShiState Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Chongqing, China.
Supeng YinState Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Chongqing, China.
Wei ShenDepartment of microbiology, College of Basic Medicin, Third Military Medical University (Army Medical University), Chongqing, China.
Jing ChenState Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Chongqing, China.
Yu ChenState Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Chongqing, China.
Yajie ChenState Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Chongqing, China.
Bo YouState Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Chongqing, China.
Yali GongState Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Chongqing, China.
Xiaoqiang LuoState Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Chongqing, China.
Cheng ZhangState Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Chongqing, China.
Zhiqiang YuanState Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Chongqing, China.
Yizhi PengState Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, Southwest Hospital, Chongqing, China. yizhipengtmmu@163.com.
Southwest Hospital · CNArmy Medical University · CN

Funding

Foundation of State Key Laboratory of Trauma, Burns and combined injury SKLZZ201708National Natural Science Foundation of China 81772073National Natural Science Foundation of China (CN) 81571896the Technological Innovation Plan in Major Fields of Southwest Hospital, Key Projects SWH2016ZDCX2001
6 · The paper itself

Abstract

A novel virulent bacteriophage, φAbp2, infecting multidrug-resistant (MDR) Acinetobacter baumannii was isolated from the wastewater of a sewage management centre at Southwest Hospital, China. Transmission electron microscopy and phylogenetic analysis revealed that φAbp2 belongs to the subfamily Peduovirinae. A one-step growth curve demonstrated that φAbp2 had a latent period of 15 min, a lysis period of 35 min, and a burst size of 222 particles per infected host cell. Moreover, φAbp2 showed a relatively broad host range in local A. baumannii, and it also exhibited tolerance over a wider range of thermal and pH conditions. Genomic sequencing revealed that φAbp2 has a circular double-stranded DNA genome with no sequence similarity to our previously isolated φAbp1. Eighty-eight putative open reading frames (ORFs) encoding 41 proteins of known function and 47 of unknown function were identified, and the G/C content was 37.84%. φAbp2 is a new member of the subfamily Peduovirinae of the family Myoviridae. Its genome sequence is very similar to that of the A. baumannii phage LZ35.

Indexed as

Genome, ViralAcinetobacter baumanniiBacteriophagesBase CompositionDrug Resistance, Multiple, BacterialMicroscopy, Electron, TransmissionMolecular Sequence AnnotationMyoviridaeOpen Reading FramesPhylogenySequence Analysis, DNAWastewaterWastewater

Identifiers

PMID30900072
PMCPMC6526140
OpenAlexW2923432541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.