Evidence map›Paper›PMID 30900052›Full record

ReviewWorld journal of microbiology & biotechnology2019

Harnessing the knowledge of protein secretion for enhanced protein production in filamentous fungi.

Xianhua Sun, Xiaoyun Su

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Optimization of mannanase expression inFrontiers in bioengineering and biotechnology · 2025
    Article
  6. Review
  7. Heterologous protein production in filamentous fungi.Applied microbiology and biotechnology · 2023
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Secretome Analysis ofInternational journal of molecular sciences · 2021
    Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Xianhua SunKey Laboratory for Feed Biotechnology of the Ministry of Agriculture, Feed Research Institute, Chinese Academy of Agricultural Sciences, No. 12 South Zhongguancun Street, Beijing, 100081, China.
Xiaoyun SuKey Laboratory for Feed Biotechnology of the Ministry of Agriculture, Feed Research Institute, Chinese Academy of Agricultural Sciences, No. 12 South Zhongguancun Street, Beijing, 100081, China. suxiaoyun@caas.cn.ORCID http://orcid.org/0000-0003-0547-9252
Chinese Academy of Agricultural Sciences · CN

Funding

Fundamental Research Funds for Central Non-profit Scientific Institution 1610382016004 and Y2017JC31National Chicken Industry Technology System of China CARS-41National Key R&D Program of China 2016YFD0501409-02National Natural Science Foundation of China Grant 31672458
6 · The paper itself

Abstract

Filamentous fungi are important microorganisms used in industrial production of proteins and enzymes. Among these organisms, Trichoderma reesei, Aspergilli, and more recently Myceliophthora thermophile are the most widely used and promising ones which have powerful protein secretion capability. In recent years, there have been tremendous achievements in understanding the molecular mechanisms of the secretory pathways in filamentous fungi. The acquired pieces of knowledge can be harnessed to enhance protein production in filamentous fungi with assistance of state-of-the-art genetic engineering techniques.

Indexed as

AspergillusCodonFungal ProteinsFungiGene Expression Regulation, FungalGenetic EngineeringGlycosylationPeptidesProtein FoldingProtein Sorting SignalsProtein TransportSaccharomycetalesSecretory PathwayTrichodermaCodonFungal ProteinsPeptidesProtein Sorting SignalsAspergilliFilamentous fungiGenetic engineeringHeterologous expressionSecretion pathwayTrichoderma reesei

Identifiers

PMID30900052
OpenAlexW2923627660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.