Evidence map›Paper›PMID 30900014›Full record

ReviewLung2019

Pulmonary Acinus: Understanding the Computed Tomography Findings from an Acinar Perspective.

Bruno Hochhegger, Felipe W Langer, Klaus Irion, Arthur Souza, José Moreira, Matteo Baldisserotto, Yana Pallaoro, Enrico Muller, Tassia Machado Medeiros, Stephan Altmayer and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Lung, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bruno HochheggerMedical Imaging Research Laboratory, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Rio Grande Do Sul, Brazil. brunoho@ufcspa.edu.br.ORCID 0000-0003-1984-4636
Felipe W LangerDepartment of Radiology and Imaging Diagnosis, Federal University of Santa Maria, Santa Maria, Brazil.
Klaus IrionDepartment of Radiology, Liverpool Heart and Chest Hospital, Thomas Dr, Liverpool, L14 3PE, UK.
Arthur SouzaDepartment of Radiology, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, Brazil.
José MoreiraMedical Imaging Research Laboratory, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Rio Grande Do Sul, Brazil.
Matteo BaldisserottoPostgraduate program, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.
Yana PallaoroMedical Imaging Research Laboratory, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Rio Grande Do Sul, Brazil.
Enrico MullerPostgraduate program, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.
Tassia Machado MedeirosPostgraduate program, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.
Stephan AltmayerMedical Imaging Research Laboratory, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Rio Grande Do Sul, Brazil.
Edson MarchioriDepartment of Radiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lung acinus is the most distal portion of the airway responsible for the gas exchange. The normal acini are not visible on conventional computed tomography (CT), but the advent of micro-CT improved the understanding of the microarchitecture of healthy acini. The comprehension of the acinar architecture is pivotal for the understanding of CT findings of diseases that involve the acini. Centriacinar emphysema, for example, presents as round areas of low attenuation due to the destruction of the most central acini with compensatory enlargement of proximal acini due to alveolar wall destruction. In pulmonary fibrosis, intralobular septal fibrosis manifests as acinar wall thickening with an overlap of acinar collapse and compensatory dilation of surrounding acini constituting the cystic disease typical of the usual interstitial pneumonia pattern. This is a state-of-the-art review to describe the acinar structure from the micro-CT perspective and display how the comprehension of the acinar structure can aid in the interpretation of its microarchitecture disruption on conventional CT.

Indexed as

HumansLungPulmonary AlveoliPulmonary EmphysemaPulmonary FibrosisTomography, X-Ray ComputedTuberculosis, PulmonaryX-Ray MicrotomographyComputerized tomographyMicro-computed tomographyPulmonary acinusSecondary pulmonary lobule

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.