ArticleUrolithiasis2020
Sex differences in the temperature dependence of kidney stone presentations: a population-based aggregated case-crossover study.
Article in Urolithiasis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Association Between Ambient Temperature and Urolithiasis: A Systematic Review and Meta-analysis.Current urology reports · 2026Pooled it
- Gender Differences in Kidney Stone Disease (KSD): Findings from a Systematic Review.Current urology reports · 2021Pooled it
- Prenatal exposure to extreme heat and autism in children.The Science of the total environment · 2026Article
- Unveiling heat vulnerability of older adults: an assessment of emergency hospital admissions in Switzerland.International journal of epidemiology · 2026Article
- Ambient Temperature and Risk of Renal Colic: A Systematic Review and Meta-analysis.Kidney medicine · 2026Article
- Environmental Heat and Renal Health Across Cosmopolitan Populations: A Scoping Review Focused on Sex-Specific Vulnerability.International journal of public health · 2026Article
- The effect of geography and climatic factors on the hospitality burden due to kidney stones in Spain 1997-2022.Open research Europe · 2026Article
- An overview of the urinary stone's disease in north of Tunisia over the past decade.World journal of urology · 2025Article
- The impact of high humidex on the risk of hospital admissions for urinary system diseases in Lanzhou, China: A time-series analysis.iScience · 2025Article
- Prevalence and Factors Associated with Kidney Stones in the Elderly Iranian Population: Findings from the Ardakan Cohort Study on Aging (ACSA).Archives of Iranian medicine · 2025Article
- Drug-induced kidney stones: a real-world pharmacovigilance study using the FDA adverse event reporting system database.Frontiers in pharmacology · 2025Article
- Sex-Specific Association of Ambient Temperature With Urine Biomarkers in Southwest Coastal Bangladesh.Kidney international reports · 2024Article
- High ambient temperature impact on the pattern of emergency-room visits due to renal colic in the Middle East.Urolithiasis · 2024Article
- Pathophysiology and Main Molecular Mechanisms of Urinary Stone Formation and Recurrence.International journal of molecular sciences · 2024Review
- Kidney Stone Prevention.Advances in nutrition (Bethesda, Md.) · 2023Review
- Epidemiology of Kidney Stones.Healthcare (Basel, Switzerland) · 2023Review
- Sex disparities and the risk of urolithiasis: a large cross-sectional study.Annals of medicine · 2022Article
- The Risk Factors for Radiolucent Nephrolithiasis among Workers in High-Temperature Workplaces in the Steel Industry.International journal of environmental research and public health · 2022Article
- Attributable risks of hospitalizations for urologic diseases due to heat exposure in Queensland, Australia, 1995-2016.International journal of epidemiology · 2022Article
- The impact of heat on kidney stone presentations in South Carolina under two climate change scenarios.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
Previous studies assumed a uniform relationship between heat and kidney stone presentations. Determining whether sex and other characteristics modify the temperature dependence of kidney stone presentations has implications for explaining differences in nephrolithiasis prevalence and improving projections of the effect of climate change on nephrolithiasis. We performed an aggregated case-crossover study among 132,597 children and adults who presented with nephrolithiasis to 68 emergency departments throughout South Carolina from 1997 to 2015. We used quasi-Poisson regression with distributed lag non-linear models to estimate sex differences in the cumulative exposure and lagged response between maximum daily wet-bulb temperatures and emergent kidney stone presentations, aggregated at the ZIP-code level. We also explored interactions by age, race, payer, and climate. Compared to 10 °C, daily wet-bulb temperatures at the 99th percentile were associated with a greater increased relative risk (RR) of kidney stone presentations over 10 days for males (RR 1.73; 95% CI 1.56, 1.91) than for females (RR 1.15; 95% CI 1.01, 1.32; interaction P < 0.001). The shape of the lagged response was similar for males and females, with the greatest risk estimated for the 2 days following high temperatures. There were weak differences by age, race, and climatic zone, and no differences by payer status. The estimated risk of presenting emergently with kidney stones within 10 days of high daily wet-bulb temperatures was substantially greater among men than women, and similar between patients with public and private insurance. These findings suggest that the higher risk among males may be due to sexually dimorphic physiologic responses rather than greater exposure to ambient temperatures.
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