Evidence map›Paper›PMID 30899767›Full record

ArticleOpen forum infectious diseases2019

Impact of Antibiotic Therapy in the Microbiological Yield of Healthcare-Associated Ventriculitis and Meningitis.

Thomas Rogers, Kevin Sok, Timothy Erickson, Elizabeth Aguilera, Susan H Wootton, Kristy O Murray, Rodrigo Hasbun

Registry-linked trialAbstract read
In one paragraph

Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06358209 (Safety and Efficacy of Ventricular Irrigation for Ventriculitis), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06358209 narecruitingnot on this mapstarted 2025, after this paper: background citation

Safety and Efficacy of Ventricular Irrigation for Ventriculitis: a Randomized Controlled Trial

TypeinterventionalSponsorRenJi HospitalRan2025 to 2028Enrolled310ConditionsCentral Nervous System InfectionsArmsVentricular irrigation
3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Review
  13. Outbreak of Meningitis in Iraq in 2023.Global pediatric health · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Review
  19. Article
  20. Ventriculitis: Infection or Inflammation.Antibiotics (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thomas RogersInfectious Disease Division, Department of Internal Medicine, McGovern Medical School at the University of Texas Health Science Center in Houston, Houston, Texas.
Kevin SokInfectious Disease Division, Department of Internal Medicine, McGovern Medical School at the University of Texas Health Science Center in Houston, Houston, Texas.
Timothy EricksonDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas.
Elizabeth AguileraInfectious Disease Division, Department of Pediatrics, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, Texas.
Susan H WoottonInfectious Disease Division, Department of Pediatrics, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, Texas.
Kristy O MurrayDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas.
Rodrigo HasbunInfectious Disease Division, Department of Internal Medicine, McGovern Medical School at the University of Texas Health Science Center in Houston, Houston, Texas.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of antibiotic therapy on the diagnosis of healthcare-associated ventriculitis and meningitis (HCAVM) is unknown. Antibiotics were administered before obtaining cerebrospinal fluid (CSF) in 217 out of 326 (66%) patients with HCAVM, and they impacted the sensitivity of the cerebrospinal fluid Gram stain and culture (

Indexed as

antibioticCSF culturehealthcare-associatedmeningitisventriculitis

Identifiers

PMID30899767
PMCPMC6422431

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.