Evidence map›Paper›PMID 30899432›Full record

ArticleOncotarget2019

DNA hypomethylation-related overexpression of SFN, GORASP2 and ZYG11A is a novel prognostic biomarker for early stage lung adenocarcinoma.

Ryan Edbert Husni, Aya Shiba-Ishii, Tomoki Nakagawa, Tomoko Dai, Yunjung Kim, Jeongmin Hong, Shingo Sakashita, Noriaki Sakamoto, Yukio Sato, Masayuki Noguchi

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. The Current Roadmap of Lung Cancer Biology, Genomics and Racial Disparity.International journal of molecular sciences · 2025
    Review
  2. Article
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  5. Article
  6. Adaptation of the Golgi Apparatus in Cancer Cell Invasion and Metastasis.Frontiers in cell and developmental biology · 2021
    Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ryan Edbert HusniDoctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.
Aya Shiba-IshiiDepartment of Diagnostic Pathology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Tomoki NakagawaDoctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.
Tomoko DaiDepartment of Diagnostic Pathology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Yunjung KimDepartment of Diagnostic Pathology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Jeongmin HongDoctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.
Shingo SakashitaDepartment of Diagnostic Pathology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Noriaki SakamotoDepartment of Diagnostic Pathology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Yukio SatoDepartment of Thoracic Surgery, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Masayuki NoguchiDepartment of Diagnostic Pathology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
University of Tsukuba · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although alteration of DNA methylation in advanced cancer has been extensively investigated, few data for early-stage lung adenocarcinoma are available. Here, we compared DNA methylation profiles between adenocarcinoma

Indexed as

DNA demethylationearly-stage lung adenocarcinomaepigeneticsGORASP2ZYG11A

Identifiers

PMID30899432
PMCPMC6422190
OpenAlexW2916222881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.