Evidence map›Paper›PMID 30899315›Full record

ArticleImmunity & ageing : I & A2019

Benthe van der Lugt, Adriaan A van Beek, Steven Aalvink, Ben Meijer, Bruno Sovran, Wilbert P Vermeij, Renata M C Brandt, Willem M de Vos, Huub F J Savelkoul, Wilma T Steegenga and 1 more

Open access · goldAbstract read
In one paragraph

Article in Immunity & ageing : I & A, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 206 citations in OpenAlex.

  1. The long-lived immune system of centenarians.Nature reviews. Immunology · 2026
    Review
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  5. Biomolecules · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article

74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Benthe van der Lugt *1Division of Human Nutrition and Health, Wageningen University and Research, Wageningen, The Netherlands.
Adriaan A van Beek *2Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Steven Aalvink4Laboratory of Microbiology, Wageningen University and Research, Wageningen, The Netherlands.
Ben Meijer3Cell Biology and Immunology Group, Wageningen University and Research, Wageningen, The Netherlands.
Bruno Sovran5Host Microbe Interactomics, Wageningen University and Research, Wageningen, The Netherlands.
Wilbert P Vermeij6Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Renata M C Brandt6Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Willem M de Vos4Laboratory of Microbiology, Wageningen University and Research, Wageningen, The Netherlands.
Huub F J Savelkoul3Cell Biology and Immunology Group, Wageningen University and Research, Wageningen, The Netherlands.
Wilma T Steegenga1Division of Human Nutrition and Health, Wageningen University and Research, Wageningen, The Netherlands.
Clara Belzer4Laboratory of Microbiology, Wageningen University and Research, Wageningen, The Netherlands.
Wageningen University & Research · NLErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of

resultsThe thickness of the colonic mucus layer increased about 3-fold after long-term

conclusionsAltogether, we show that supplementation with

Indexed as

AgingAkkermansia muciniphilaIntestinal barrierIntestinal immunityMucus layer

Identifiers

PMID30899315
PMCPMC6408808
OpenAlexW2934490979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.