Evidence map›Paper›PMID 30899306›Full record

ArticleArchives of medical science : AMS2019

Polymorphisms in

Tairine Zara-Lopes, Ana Lívia Silva Galbiatti-Dias, Márcia M Urbanin Castanhole-Nunes, João Armando Padovani-Júnior, José Victor Maniglia, Erika Cristina Pavarino, Eny Maria Goloni-Bertollo

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Review
  7. Analysis of major otosclerosis-associated variants inArchives of medical science : AMS · 2024
    Article
  8. Common Variants in One-Carbon Metabolism Genes (International journal of molecular sciences · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Diagnostic and prognostic value ofArchives of medical science : AMS · 2023
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tairine Zara-LopesGenetics and Molecular Biology Research Unit - UPGEM, Molecular Biology Department, São José do Rio Preto Medical School - FAMERP, São Paulo, Brazil.
Ana Lívia Silva Galbiatti-DiasGenetics and Molecular Biology Research Unit - UPGEM, Molecular Biology Department, São José do Rio Preto Medical School - FAMERP, São Paulo, Brazil.
Márcia M Urbanin Castanhole-NunesGenetics and Molecular Biology Research Unit - UPGEM, Molecular Biology Department, São José do Rio Preto Medical School - FAMERP, São Paulo, Brazil.
João Armando Padovani-JúniorOtorhinolaryngology and Head and Neck Surgery Department, São José do Rio Preto Medical School - FAMERP, São Paulo, Brazil.
José Victor ManigliaOtorhinolaryngology and Head and Neck Surgery Department, São José do Rio Preto Medical School - FAMERP, São Paulo, Brazil.
Erika Cristina PavarinoGenetics and Molecular Biology Research Unit - UPGEM, Molecular Biology Department, São José do Rio Preto Medical School - FAMERP, São Paulo, Brazil.
Eny Maria Goloni-BertolloGenetics and Molecular Biology Research Unit - UPGEM, Molecular Biology Department, São José do Rio Preto Medical School - FAMERP, São Paulo, Brazil.
Faculdade de Medicina de São José do Rio Preto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPolymorphisms in genes coding enzymes involved in folate metabolism may cause alterations in this metabolic pathway and contribute to carcinogenesis, because folate is essential for DNA synthesis, methylation and repair. The objective of this study was to investigate the association of MATERIAL AND

methodsThe study is a case-control analysis with a total of 462 individuals (151 patients and 311 controls). Polymerase chain reaction-restriction fragment length polymorphism technique was used for genotyping. The χ

resultsThe polymorphisms analysis revealed an association between the

conclusions

Indexed as

genesgenetic polymorphismthyroid cancer

Identifiers

PMID30899306
PMCPMC6425207
OpenAlexW2911986483

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.