ReviewFrontiers in plant science2019
Spatial and Temporal Profile of Glycine Betaine Accumulation in Plants Under Abiotic Stresses.
Review in Frontiers in plant science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 1 of them a synthesis that pooled it.
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Who cites it
136 citing papers in PubMed, 1 synthesis or guideline pooled it, 319 citations in OpenAlex.
- Emerging role of osmoprotectant glycine betaine to mitigate heavy metals toxicity in plants: a systematic review.Biologia futura · 2024Pooled it
- Genotype performance, biochemical and anatomical response of two mango rootstocks to glycine betaine and algae extract under salinity stress.BMC plant biology · 2026Article
- Valorization ofBiotech (Basel (Switzerland)) · 2026Article
- Compatible Solute Variation and Stress Adaptation in Native Qatari Plants: Focus on Proline.Life (Basel, Switzerland) · 2026Review
- Heat-Stress Memory Modulates Antioxidant Metabolism and Increases Senecionine Biosynthesis Across Developmental Stages ofPlants (Basel, Switzerland) · 2026Article
- Foliar L-arginine and seaweed extract mitigate salinity stress in Calendula officinalis L. by enhancing physiological and biochemical performance.BMC plant biology · 2026Article
- Glycine betaine alleviates salt stress in tomato by enhancing the chlorophyll synthesis pathway, photosynthesis, and regulating mBMC plant biology · 2026Article
- Evaluation of the effects of hydrogel and glycine betaine application on growth, physiological characteristics and yield of peanut under water deficit.BMC plant biology · 2026Article
- Sustainable and innovative electrochemical approach for quantifying glycine betaine in bacterial cultures.RSC advances · 2026Article
- Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications.Chemical reviews · 2026Review
- Drought tolerance mechanisms across C3 and C3-C4 intermediate photosynthetic types revealed by physiological and gene expression profiling.Scientific reports · 2026Article
- Constructing pathways for glycine betaine in cross-domain ecological restoration: a bibliometric analysis.PeerJ · 2026Article
- The regulatory roles of flavonoids, melatonin, and glycine betaine in plant salt stress response.Frontiers in plant science · 2026Review
- Exogenous glycine betaine alleviates dynamic physiological and transcriptomic responses inFrontiers in plant science · 2026Article
- Innovative strategies for salinity stress management in Mango nursery plants: Agrobacterium fabrum and Glycine betaine approach.BMC plant biology · 2025Article
- Overexpression ofBiomolecules · 2025Article
- Chromosome-level genome assembly of Albizia odoratissima and effect of flavonoid metabolic pathways under drought stress.BMC plant biology · 2025Article
- Investigating the effect of foliar spraying of zinc nanoparticles and biostimulants on modulating the effect of water deficit stress in sugar beet by using Integrated Biomarker Response Version 2.Scientific reports · 2025Article
- Methyl jasmonate enhances boron toxicity tolerance in strawberry (Fragaria × Ananassa 'Albion') by modulating plant growth, antioxidant defenses, and biochemical responses.BMC plant biology · 2025Article
- Effect of drying conditions on the preservation of selected bioactive compounds in Moringa oleifera aqueous extract: acetic acid, butyric acid, γ-aminobutyric acid, salicin, and glycine.BMC plant biology · 2025Article
76 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several halophytes and a few crop plants, including Poaceae, synthesize and accumulate glycine betaine (GB) in response to environmental constraints. GB plays an important role in osmoregulation, in fact, it is one of the main nitrogen-containing compatible osmolytes found in Poaceae. It can interplay with molecules and structures, preserving the activity of macromolecules, maintaining the integrity of membranes against stresses and scavenging ROS. Exogenous GB applications have been proven to induce the expression of genes involved in oxidative stress responses, with a restriction of ROS accumulation and lipid peroxidation in cultured tobacco cells under drought and salinity, and even stabilizing photosynthetic structures under stress. In the plant kingdom, GB is synthesized from choline by a two-step oxidation reaction. The first oxidation is catalyzed by choline monooxygenase (CMO) and the second oxidation is catalyzed by NAD+-dependent betaine aldehyde dehydrogenase. Moreover, in plants, the cytosolic enzyme, named
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.